Bioink Deposition
Bioink Deposition - Related Videos
08:34
Bioprinting Cellularized Constructs Using a Tissue-specific Hydrogel Bioink
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Cited by 59 •
2016
We describe a set of protocols that together provide a tissue-mimicking hydrogel bioink with which functional and viable 3-D tissue constructs can be bioprinted for use in in vitro screening applications.
02:33
Phase Transitions: Sublimation and Deposition
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2020
Some solids can transition directly into the gaseous state, bypassing the liquid state, via a process known as sublimation. At room temperature and standard pressure, a piece of dry ice (solid CO2) sublimes, appearing to gradually disappear without ever forming any liquid. Snow and ice sublimate at temperatures below the melting point of water, a slow process that may be accelerated by winds and the reduced atmospheric pressures at high altitudes. When solid iodine is warmed, the solid sublimes...
10:52
Formation of Thick Dense Yttrium Iron Garnet Films Using Aerosol Deposition
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Cited by 7 •
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This report describes the use of a custom-built system to perform aerosol deposition of thick films of yttrium iron garnet onto sapphire substrates at RT. The deposited films are characterized using scanning electron microscopy, profilometry, and ferromagnetic resonance to give a representative overview of the capabilities of the technique.
09:56
Layer-by-layer Collagen Deposition in Microfluidic Devices for Microtissue Stabilization
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Cited by 7 •
2015
The creation of functional microtissues within microfluidic devices requires the stabilization of cell phenotypes by adapting traditional cell culture techniques to the limited spatial dimensions in microdevices. Modification of collagen allows the layer-by-layer deposition of ultrathin collagen assemblies that can stabilize primary cells, such as hepatocytes, as microfluidic tissue models.
08:25
Chemical Vapor Deposition of an Organic Magnet, Vanadium Tetracyanoethylene
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Cited by 15 •
2015
We present the synthesis of the organic-based ferrimagnet vanadium tetracyanoethylene (V[TCNE]x, x~2) via low temperature chemical vapor deposition (CVD). This optimized recipe yields an increase in Curie temperature from 400 K to over 600 K and a dramatic improvement in magnetic resonance properties.
FAQs
Viscosity affects how a bioink forms and maintains a deposited filament. In Bioink Deposition, it must be considered with nozzle-based patterning because the material’s flow behavior influences shape fidelity. This makes viscosity a central engineering variable when designing three-dimensional tissue constructs with consistent geometry and architecture.
Shear stress matters because it is one of the deposition conditions that can influence cell survival. Engineers therefore evaluate it alongside viscosity, print speed, and the selected deposition system. Managing these interacting variables helps balance accurate filament formation with the biological requirement to preserve viable cells within the developing construct.
Crosslinking and print speed both influence how deposited material becomes a stable, accurately shaped structure. Their effects are evaluated through outcomes such as filament formation and shape fidelity, while cell survival remains an additional consideration. Adjusting these variables allows engineers to tune the balance between geometric control and biological compatibility.
A typical workflow patterns a bioink through a nozzle or another printing system, placing material according to a planned architecture. The construct is built layer by layer, while engineers consider viscosity, shear stress, crosslinking, and print speed. These process variables determine whether the resulting structure retains the intended filament arrangement and shape.
Engineers use this approach to fabricate scaffolds, organoid-supporting constructs, and tissue models with designed architectures. These applications require controlled placement of cell-containing or cell-compatible materials rather than an unstructured mass. The resulting geometry provides a defined platform for studying cell behavior and for developing constructs relevant to regenerative medicine.
Designed deposited architectures can support controlled studies of cell behavior and the creation of tissue models for disease modeling. The same engineering capability contributes to research in regenerative medicine and personalized therapies. Its value lies in connecting controllable three-dimensional structure with biological investigation, rather than only producing a physical scaffold.