Petrolatum Gauze

Petrolatum gauze is a soft, nonadherent wound dressing coated with petrolatum that protects damaged tissue while supporting a moist healing environment. Its occlusive, lubricating layer limits direct contact between the wound and the dressing, reducing disruption of new tissue and helping prevent the dressing from sticking during removal. In immunology and infection care, petrolatum gauze can cover burns, abrasions, lacerations, and surgical wounds, providing a physical barrier against environmental contamination while reducing tissue trauma that may compromise local defenses. Because it does not replace antimicrobial treatment or aseptic wound care, clinicians must monitor for inflammation, drainage, and other signs of infection.

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Research

JoVE EoE - Immunotherapy

A Technique for Human Skin Grafting in a Mouse Model

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2025

This video demonstrates a method for grafting human skin onto an immunodeficient mouse with a suppressed neutrophil response. The method involves applying human split-thickness skin to the mouse's graft bed, sealing it, and covering it for recovery. Eventually, the human skin adheres to the mouse's skin, establishing vascularization and circulation, resulting in a successful skin xenograft.

Portal Vein Injection: A Method to Study Cancer Metastasis to the Liver

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2023

This video describes a surgical procedure to deliver mammary tumor cells to the murine liver via portal vein injection. This model permits the investigation of late stages of liver metastasis.

Targeting Liver Tumors with Oncolytic Viruses via the Hepatic Artery

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2025

The video demonstrates locoregional delivery of oncolytic viruses through hepatic arterial injection as a therapeutic approach for hepatocellular carcinoma. These viruses selectively replicate in tumor cells, inducing cell lysis and releasing tumor cell-associated antigens. This process triggers immunogenic cell death, inducing an anti-tumor response.

Education

JoVE Science Education - Clinical Skills

Discontinuing Intravenous Fluids and a Peripheral Intravenous Line

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2023

Source: Madeline Lassche, MSNEd, RN and Katie Baraki, MSN, RN, College of Nursing, University of Utah, UT Intravenous (IV) fluid administration and peripheral IV catheters (PIVs) may be discontinued for a number of reasons. The most common reason for discontinuing IV fluids is that the patient has returned to normal body fluid volume (euvolemia) and is able to maintain adequate oral fluid intake or is being discharged from the hospital. In addition, the Centers for Disease Control Guidelines...

Transarterial Administration of Oncolytic Viruses for Locoregional Therapy of Orthotopic HCC in Rats

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Cited by 3 •

2016

Oncolytic virotherapies are under development as novel therapeutics for the treatment of hepatocellular carcinoma (HCC). Here we describe a method for locoregional therapy of HCC via hepatic arterial administration of oncolytic virus.

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