C2 Vertebra Injury
C2 Vertebra Injury - Related Videos
01:30
General Structure of a Vertebra
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2025
A typical vertebra, with the exception of the sacrum and coccyx, consists of a body, a vertebral arch, and seven different projections termed processes. The anterior portion of the vertebrae, the body, supports about half the body’s weight. The vertebral bodies progressively increase in size and thickness from the cervical region to the lumbar region of the vertebral column. The intervertebral discs present between the bodies of adjacent vertebrae firmly unites them, forming a continuous column.
04:38
Modeling Sensory Axon Regeneration in a Rat Using Dorsal Root Ganglion Injection and Dorsal Root Crush Injury
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2025
Source: Cheah, M., et al. Dorsal Root Ganglion Injection and Dorsal Root Crush Injury as a Model for Sensory Axon Regeneration. J. Vis. Exp. (2017).This video demonstrates a step-by-step procedure for injecting a viral suspension into the dorsal root ganglia (DRGs) and inducing a controlled axonal injury via a dorsal root crush in an anesthetized rat. The protocol involves exposing the DRGs, delivering a growth-promoting viral vector to facilitate axonal regeneration, and severing axonal...
09:24
A Novel Vertebral Stabilization Method for Producing Contusive Spinal Cord Injury
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Cited by 20 •
2015
Vertebral stabilization is necessary for minimizing variability, and for producing consistent experimental spinal cord injuries. Using a customized stabilizing apparatus in conjunction with the NYU/MASCIS impactor device, we have demonstrated here the proper equipment and procedure for generating reproducible hemi-contusive cervical (C5) spinal cord injuries in adult rats.
09:48
Dorsal Root Ganglion Injection and Dorsal Root Crush Injury as a Model for Sensory Axon Regeneration
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Cited by 9 •
2017
This protocol presents the use of a dorsal root ganglion (DRG) injection with a viral vector and a concurrent dorsal root crush injury in an adult rat as a model to study sensory axon regeneration. This model is suitable for investigating the use of gene therapy to promote sensory axon regeneration.
07:28
Controlled Cervical Laceration Injury in Mice
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Cited by 17 •
2013
A novel technique to create a reproducible in vivo model of cervical spinal cord laceration injury in the mouse is described. This technique is based on spine stabilization by fixation of the cervical facets and laceration of the spinal cord using an oscillating blade with an accuracy of ±0.01 mm.
FAQs
The injury pattern reflects how force is transmitted through the upper cervical spine. Axial loading can produce compression, whereas hyperextension or flexion can shift stresses across the vertebral body, pars interarticularis, or odontoid process. Identifying the dominant mechanism helps clinicians anticipate displacement and judge whether spinal alignment may be unstable.
Instability matters because displaced bone or disrupted alignment can narrow the space around neural structures and compromise upper spinal cord function. The risk is not determined by pain alone; clinicians also consider neurological findings and the injury pattern. Recognizing this relationship supports timely immobilization and treatment planning.
Computed tomography defines the bony damage, making it useful for evaluating fracture location and alignment. Magnetic resonance imaging adds information about the spinal cord, discs, and ligaments, which may not be fully characterized by bone-focused imaging. Used together, these studies support classification and help determine the extent of structural and neural involvement.
The initial evaluation combines the trauma mechanism with pain and neurological findings. This approach helps clinicians identify possible instability and detect evidence of neural compromise. Imaging then refines the assessment: computed tomography characterizes bone injury, while magnetic resonance imaging examines the cord, discs, and ligaments.
Classification connects the observed structural damage with its likely stability and neurological risk. Based on this assessment, care may involve immobilization, surgical stabilization, or monitored nonoperative management. The choice depends on the defined injury pattern and alignment rather than on symptoms considered in isolation, allowing treatment to address both immediate safety and mechanical stability.
Assessment provides more than an anatomic description of the trauma. Neurological findings, spinal alignment, and imaging-defined damage help clinicians estimate recovery and the possibility of long-term disability. This prognostic information supports monitoring and treatment decisions while clarifying how structural instability or neural compromise may influence the eventual outcome.