Cardiac Anatomy Assessment
Cardiac Anatomy Assessment - Related Videos
08:09
Echocardiographic Assessment of Cardiac Anatomy and Function in Adult Rats
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Cited by 10 •
2019
A non-invasive protocol for transthoracic echocardiography assessment of cardiac anatomy and function for adult rats is presented in the current study. The heart valves, all four cardiac chambers and the ascending aorta, aortic arch and descending aorta are studied in detail.
11:10
Respirometric Oxidative Phosphorylation Assessment in Saponin-permeabilized Cardiac Fibers
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Cited by 32 •
2011
Saponin-permeabilized fiber preparation in conjunction with respirometric oxidative phosphorylation analysis provides integrative assessment of mitochondrial function. Mitochondrial respiration in physiological and pathological states can reflect various regulatory influences including mitochondrial interactions, morphology and biochemistry.
01:27
Anatomy of the Heart
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2019
The human heart is made up of three layers of tissue that are surrounded by the pericardium, a membrane that protects and confines the heart. The outermost layer, closest to the pericardium, is the epicardium. The pericardial cavity separates the pericardium from the epicardium. Beneath the epicardium is the myocardium, the middle layer, and the endocardium, the innermost layer. There are four chambers of the heart: the right atrium, the right ventricle, the left atrium, and the left ventricle.
05:04
In vitro Assessment of Cardiac Reprogramming by Measuring Cardiac Specific Calcium Flux with a GCaMP3 Reporter
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Cited by 4 •
2022
We describe here, the establishment and application of an Tg(Myh6-cre)1Jmk/J /Gt(ROSA)26Sortm38(CAG-GCaMP3)Hze/J (referred to as αMHC-Cre/Rosa26A-Flox-Stop-Flox-GCaMP3 below) mouse reporter line for cardiac reprogramming assessment. Neonatal cardiac fibroblasts (NCFs) isolated from the mouse strain are converted into induced cardiomyocytes (iCMs), allowing for convenient and efficient evaluation of reprogramming efficiency and functional maturation of iCMs via calcium (Ca2+) flux.
11:38
Assessment of Cardiac Function and Energetics in Isolated Mouse Hearts Using 31P NMR Spectroscopy
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Cited by 36 •
2010
Langendorff-mode isolated heart perfusion, in conjunction with 31P NMR spectroscopy, combines the fields of biochemistry and physiology into one experiment. The protocol allows for the dynamic measurement of high energy phosphate content and turnover in the heart while concurrently monitoring physiologic function. When performed correctly, this is a valuable technique in the assessment of cardiac energetics.
FAQs
Echocardiography provides anatomical imaging that can show cardiac structures while also assessing blood flow. This combination helps clinicians relate the appearance of chambers, valves, walls, and great vessels to how the heart is functioning. It is especially useful when an assessment must identify structural alterations that may contribute to valve disease or congenital defects.
Spatial relationships help clinicians interpret how the chambers, valves, walls, and great vessels are arranged relative to one another. An assessment can therefore identify not only an abnormal structure but also an altered anatomical relationship. This information supports accurate interpretation of congenital abnormalities and improves the connection between imaging findings and surgical observations.
Clinical examination and anatomical imaging provide complementary information rather than serving identical purposes. Examination contributes to the clinical evaluation, whereas imaging allows direct visualization of cardiac structures and, through echocardiography, assessment of blood flow. Using these approaches together gives clinicians a broader basis for recognizing whether cardiac anatomy is normal or altered.
A complete assessment considers multiple structural elements, including chambers, valves, walls, great vessels, and their spatial relationships. Examining these components together can reveal broader patterns of alteration rather than focusing on one isolated finding. That wider perspective is important when evaluating congenital defects, valve disease, or other changes affecting cardiac structure.
The evaluation begins with clinical examination and proceeds, when needed, to anatomical imaging. Imaging is used to visualize the heart’s chambers, valves, walls, great vessels, and spatial relationships, while echocardiography can also assess blood flow. Findings are then interpreted to determine whether anatomy is normal or altered and to inform clinical decisions.
It is particularly useful when clinicians need to identify congenital defects or valve disease, plan treatment, or follow changes over time. Structural findings can guide decisions about intervention and provide a basis for judging whether disease has progressed or responded to treatment. The assessment therefore connects anatomical information with diagnosis and ongoing patient management.
Before or after an intervention, anatomical findings can help clinicians interpret surgical observations and relate them to the heart’s actual structure. Beyond clinical care, these evaluations contribute to research on cardiovascular development and dysfunction. By documenting normal and altered anatomy, assessment supports both practical interpretation of procedures and investigation of how cardiac abnormalities arise or persist.