Lung Biopsy Technique

Lung biopsy is a medical procedure that obtains a sample of lung tissue for microscopic and laboratory analysis, helping identify the cause of abnormal imaging findings or respiratory disease. Depending on lesion location and patient condition, clinicians may collect tissue through bronchoscopy, a needle passed through the chest wall, or surgical removal; guidance from imaging or direct visualization helps target the specimen while limiting injury to surrounding structures. Pathologists examine the sample for infection, inflammation, fibrosis, or malignancy. In medicine, lung biopsy supports diagnosis, disease classification, treatment planning, and assessment of uncertain pulmonary abnormalities.

Lung Biopsy Technique - Related Videos

Research

JoVE Journal - Medicine

A Technique for Subcutaneous Abdominal Adipose Tissue Biopsy via a Non-diathermy Method

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Cited by 7 •

2017

We standardized an abdominal adipose tissue biopsy using a non-diathermy method performed under local anesthesia. Three cases of excessive post-operation bleeding out of 115 operations (2.61%) occurred.We conclude that an abdominal adipose tissue surgical biopsy using a non-diathermy method can be safely applied to healthy men.

Technique of Conjunctival Biopsy and Direct Immunofluorescence for Diagnosing Mucous Membrane Pemphigoid

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2025

Here, we present a protocol for harvesting and processing conjunctival biopsy to identify mucous membrane pemphigoid.

Exosomal miRNA Analysis in Non-small Cell Lung Cancer (NSCLC) Patients' Plasma Through qPCR: A Feasible Liquid Biopsy Tool

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Cited by 59 •

2016

This protocol describes the feasibility to perform miRNA profiling in exosomes, released in plasma of NSCLC patients, through a commercial exosome isolation kit with Proteinase K and RNAse treatments, in order to avoid circulating miRNAs contamination and evaluate their biomarker features in NSCLC.

Research

JoVE Journal - Medicine
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The Bovine Lung in Biomedical Research: Visually Guided Bronchoscopy, Intrabronchial Inoculation and In Vivo Sampling Techniques

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Cited by 18 •

2014

This article describes bronchoscopic techniques in the bovine lung under experimental conditions, i.e. bronchoscopically guided inoculation, bronchoalveolar lavage, bronchial brushing, and transbronchial lung biopsy.

Research

JoVE Journal - Biology
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Bovine Mammary Gland Biopsy Techniques

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Cited by 7 •

2018

This article presents a bovine mammary gland biopsy using core and needle biopsy tools. Harvested tissue can be used for cell culture or to assess mammary physiology and metabolism including gene expression, protein expression, protein modifications, immunohistochemistry, and metabolite concentrations.

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