Minimum Lumen Area

Minimum lumen area (MLA) is the smallest cross-sectional area of a blood-vessel lumen measured along a stenotic or treated segment, providing an anatomical indicator of potential flow limitation. In intravascular ultrasound or optical coherence tomography, a catheter acquires sequential cross-sectional images, and clinicians trace the inner vessel boundary to calculate the narrowest lumen area in square millimeters. In medicine, MLA helps characterize coronary artery disease, assess lesion severity, guide decisions about revascularization, and evaluate stent expansion after implantation. Interpreted with clinical findings and other physiological measurements, it supports more consistent diagnosis, procedural planning, and treatment assessment.

Minimum Lumen Area - Related Videos

Research

JoVE EoE - Bacterial Growth and Techniques

Localized Delivery of Bacteria into the Intestinal Lumen of a Zebrafish Larva Using Microinjection

0 Views •

2025

Source: Li, J. et al. Development of a Larval Zebrafish Infection Model for Clostridioides difficile. J. Vis. Exp. (2020)This video demonstrates the microinjection-based delivery of fluorescently labeled Clostridioides difficile into the intestinal lumen of an anesthetized zebrafish larva. It outlines the steps involved in larval preparation, bacterial injection, and fluorescence microscopy–based confirmation of bacterial localization within the intestine.

Quantification of Group B Streptococcus Load in the Mouse Vaginal Lumen via Swabbing and Chromogenic Culture

0 Views •

2026

Source: Patras, K. A. & Doran, K. S. A Murine Model of Group B Streptococcus Vaginal Colonization. J. Vis. Exp. (2016)This video demonstrates the quantification of vaginal Group B Streptococcus (GBS) load in a mouse model using swabbing and chromogenic culture. It outlines the steps involved in sample collection, plating, and colony counting to quantify GBS load in the mouse vaginal lumen.

Education

JoVE Core - Calculus

Local Maximum and Minimum Values

0 Views •

2026

In multivariable calculus, a function of two variables can exhibit local maximum or minimum values at certain points on its surface. A local maximum occurs when the function's value at a point is greater than at all nearby points, while a local minimum occurs when the function’s value is less than at all nearby locations. These points are referred to as local extrema and are of central importance in optimization problems.Local extrema are found at critical points, where the surface becomes...

Research

JoVE Journal - Bioengineering
Free Sample

A Novel Cell Injection Method with Minimum Invasion

0 Views •

2023

This method eliminates any major invasion during cell injections caused by the cell suspension solution.

Minimum Burning Pressures of Water-based Emulsion Explosives

0 Views •

2017

We present an apparatus based on hot-wire ignition in a pressurized enclosure and an associated methodology to measure the minimum pressure required to induce sustained combustion in water-based emulsion explosives. This method improves product characterization to allow one to use them more safely during pumping and mixing operations.

View All Results

FAQs

Related Topics