Percutaneous Mitral Repair

Percutaneous mitral repair is a minimally invasive treatment that improves mitral valve function without open-heart surgery, primarily for patients with significant mitral regurgitation who face elevated surgical risk. During transcatheter edge-to-edge repair, clinicians guide a catheter through the venous system and across the interatrial septum, then grasp and approximate the mitral leaflets with a repair device to reduce backward blood flow. The procedure can relieve symptoms such as breathlessness, improve forward cardiac output, and support recovery in selected patients with degenerative or functional mitral regurgitation. Imaging guidance, especially echocardiography, helps clinicians position the device and assess the immediate result.

Percutaneous Mitral Repair - Related Videos

Research

JoVE Journal - Medicine

Fully Endoscopic Mitral Valve Repair with Percutaneous Cannulation of Groin Vessels

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2023

This protocol demonstrates in detail how to perform fully endoscopic mitral valve surgery (EMS) with percutaneous cannulation of the groin vessels, using a percutaneous plug-based vascular closure device. Fundamental steps and useful instructions are described in detail for each step.

A Simplified Stepwise Approach to Echo Guidance during Percutaneous Mitral Valve Repair

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2021

This protocol presents in detail how to perform real-time echocardiographic guidance during transcatheter mitral valve repair. The fundamental views and the necessary measurements are described for each stage of the procedure.

Education

JoVE Science Education - Clinical Skills

Percutaneous Cricothyrotomy

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2023

Source: James W Bonz, MD, Emergency Medicine, Yale School of Medicine, New Haven, Connecticut, USA A surgical airway procedure is indicated when other forms of endotracheal intubation have failed and ventilation is worsening or not possible. This is the feared "can't intubate, can't ventilate" scenario, and in the emergency setting, cricothyrotomy is the surgical procedure of choice. Cricothyrotomy is preferred over tracheotomy because of the lower risk of complications, the predictable anatomy...

Optimized Protocol for the Extraction of Proteins from the Human Mitral Valve

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2017

The protein composition of the human mitral valve is still partially unknown, because its analysis is complicated by low cellularity and therefore by low protein biosynthesis. This work provides a protocol to efficiently extract protein for the analysis of the mitral valve proteome.

Assessment of Neuromuscular Function Using Percutaneous Electrical Nerve Stimulation

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Cited by 30 •

2015

We present a protocol to assess changes in neuromuscular function. Percutaneous electrical nerve stimulation is a non-invasive method that evokes muscular responses. Electrophysiological and mechanical properties of these responses permit the evaluation of neuromuscular function from brain to muscle (supra-spinal, spinal and peripheral levels).

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