Lever Pressing

Lever pressing is a learned motor behavior in which an animal presses a mechanical lever to produce a defined consequence, making it a widely used model of action and decision-making in neuroscience. In operant conditioning experiments, a press may deliver food, water, electrical stimulation, or a sensory cue, allowing researchers to measure how reinforcement, motivation, and task demands alter response rate and timing. By pairing behavior with neural recordings, pharmacological manipulations, or targeted stimulation, investigators can examine brain circuits involved in reward, learning, movement, and habit formation. Lever-pressing paradigms also support studies of addiction, behavioral flexibility, and the effects of neurological disease or therapeutic interventions.

Lever Pressing - Related Videos

Research

JoVE Journal - Engineering

Measurement of Chladni Mode Shapes with an Optical Lever Method

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2020

A simple method of measuring the Chladni mode shape on an elastic plate by the principle of an optical lever is proposed.

Measuring the Interaction Force Between a Droplet and a Super-hydrophobic Substrate by the Optical Lever Method

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2019

The protocol aims to investigate the interaction between droplets and super-hydrophobic substrates in the air. This includes calibrating the measurement system and measuring the interaction force at super-hydrophobic substrates with different grid fractions.

Press Needle: A Traditional Chinese Medicine Therapy for Myopia Patients with Dry Eye

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Cited by 2 •

2024

Here, we present a protocol to standardize the operation of acupuncture in the treatment of myopia with dry eye.

Research

JoVE Journal - Behavior
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Signal Attenuation as a Rat Model of Obsessive Compulsive Disorder

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Cited by 3 •

2015

The goal of the protocol described in this paper is to induce compulsive-like behavior in rats for the study of obsessive-compulsive disorder (OCD). This behavior is precipitated by attenuating a signal indicating that a lever-press response was effective in producing food.

A Protocol for Measuring Cue Reactivity in a Rat Model of Cocaine Use Disorder

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Cited by 6 •

2018

Cue reactivity is conceptualized as sensitivity to cues linked with drug-taking experiences that contribute to craving and relapse in abstinent humans. Cue reactivity is modeled in rats by measuring attentional orientation toward drug-associated cues that results in appetitive approach behavior in a cue reactivity test following self-administration and forced abstinence.

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