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Evaluation of Nanoparticle Uptake in Tumors in Real Time Using Intravital Imaging
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Evaluation of Nanoparticle Uptake in Tumors in Real Time Using Intravital Imaging

Article DOI: 10.3791/2808-v • 08:04 min • June 21st, 2011
June 21st, 2011 •
1, 2, 2, 3, 2,4
1Department of Medical Biophysics, University of Western Ontario, 2London Regional Cancer Program, London Health Science Centre, 3Department of Pathology, Vanderbilt University, 4Translational Prostate Cancer Research Group, London Health Science Centre

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We present a novel approach to quantify nanoparticle localization in the vasculature of human xenografted tumors using dynamic, real-time intravital imaging in an avian embryo model.

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Nanoparticle Uptake Tumors Intravital Imaging Xenograft Model High-resolution Imaging Chicken Embryo Model Tumor Vasculature Nanoparticle Analysis Cowpea Mosaic Virus (CPMV) Near-infrared Fluorescent Dyes Polyethylene Glycol Polymers (PEG) Intravenous Administration
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