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Protocols for Assessing Radiofrequency Interactions with Gold Nanoparticles and Biological Systems for Non-invasive Hyperthermia Cancer Therapy

Article DOI: 10.3791/50480-v • 10:52 min • August 28th, 2013
August 28th, 2013 •
1,2, 1,2, 1, 1, 1,3
1Department of Surgical Oncology, University of Texas M.D. Anderson Cancer Center, 2Department of Chemistry, Rice University, 3Mechanical Engineering and Materials Science, Rice University

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Summary
Automatic Translation

We describe the protocols used to investigate the interactions of 13.56 MHz radiofrequency (RF) electric-fields with gold nanoparticle colloids in both non-biological and biological systems (in vitro/vivo). These interactions are being investigated for applications in cancer therapy.

Tags

Assessing Radiofrequency Interactions Gold Nanoparticles Biological Systems Non-invasive Hyperthermia Cancer Therapy RF Electric-fields Minimal Toxicity Viable Means Internalized Nanoparticles (NPs) Heat Liberation Cell Necrosis Non-biological Systems Highly-concentrated NP Colloids In Vitro Experiments Cancer Cells Bulk Media Heating Artifacts Data Obscuring In Vivo Mouse Models Ectopic Hepatic Cancer Tumors
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