Hochstereoselektive Synthese von 1,6-Ketoester durch Ionische Flüssigkeiten vermittelte: Ein Dreikomponentenreaktion zur raschen Zugang zu einer neuen Klasse von niedermolekularen Gelbildner
9,601 Views
•
06:31 min
•
November 27, 2015
DOI:
Summary
Automatically generated
Ionic liquids (ILs) mediate fast, simple and cheap access to 1,6-ketoesters in high diastereoselectivities and good yields. The reaction protocol is robust and the 1,6-ketoesters can be obtained in gram scale after a simple filtration protocol. Moreover, the 1,6-ketoesters are potent gelators in hydrocarbon solvents.
Verwandte Videos
09:14
Enzymatic Cascade Reactions for the Synthesis of Chiral Amino Alcohols from L-lysine
Verwandte Videos
12077 Views
08:12
A Two-Step Protocol for Umpolung Functionalization of Ketones Via Enolonium Species
Verwandte Videos
9949 Views
09:54
Chemoselective Preparation of 1-Iodoalkynes, 1,2-Diiodoalkenes, and 1,1,2-Triiodoalkenes Based on the Oxidative Iodination of Terminal Alkynes
Verwandte Videos
7671 Views
06:52
Synthesis of Esters Via a Greener Steglich Esterification in Acetonitrile
Verwandte Videos
35625 Views
10:17
Efficient Construction of Drug-like Bispirocyclic Scaffolds Via Organocatalytic Cycloadditions of α-Imino γ-Lactones and Alkylidene Pyrazolones
Verwandte Videos
6892 Views
07:50
Efficient Synthesis of All-Carbon Quaternary Centers via the Conjugate Addition of Functionalized Monoorganozinc Bromides
Verwandte Videos
9232 Views
07:36
Versatile CO2 Transformations into Complex Products: A One-pot Two-step Strategy
Verwandte Videos
7974 Views
06:31
Organocatalysis
Verwandte Videos
17032 Views
01:10
α-Alkylation of Ketones via Enolate Ions
Verwandte Videos
3039 Views
01:07
Alkylation of β-Ketoester Enolates: Acetoacetic Ester Synthesis
Verwandte Videos
3298 Views
Read Article
Cite this Article
Sundén, H., Ta, L., Axelsson, A. Highly Stereoselective Synthesis of 1,6-Ketoesters Mediated by Ionic Liquids: A Three-component Reaction Enabling Rapid Access to a New Class of Low Molecular Weight Gelators. J. Vis. Exp. (105), e53213, doi:10.3791/53213 (2015).
Copy