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Protokoll für die Synthese von<em> Ortho</em> -trifluoromethoxylated Anilin-Derivate
Protocol for the Synthesis of <em>Ortho</em>-trifluoromethoxylated Aniline Derivatives
JoVE Journal
Chemie
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JoVE Journal Chemie
Protocol for the Synthesis of Ortho-trifluoromethoxylated Aniline Derivatives

Protokoll für die Synthese von<em> Ortho</em> -trifluoromethoxylated Anilin-Derivate

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08:43 min

January 19, 2016

DOI:

08:43 min
January 19, 2016

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Summary

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An operationally simple procedure for the synthesis of ortho-trifluoromethoxylated aniline derivatives via a two-step sequence of O-trifluoromethylation of N-aryl-N-hydroxyacetamide followed by thermally induced intramolecular OCF3-migration is reported.

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