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Generation of a Chronic Obstructive Pulmonary Disease Model in Mice by Repeated Ozone Exposure

Article DOI: 10.3791/56095-v • 08:17 min • August 25th, 2017
August 25th, 2017 •
1,2, 3, 3, 1,2
1Cellular Biomedicine Group, Shanghai, 2Cellular Biomedicine Group, Cupertino, 3Department of Respiratory Medicine, Shanghai General Hospital, Shanghai Jiaotong University

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Summary
Automatic Translation

This study describes the successful generation of a new chronic obstructive pulmonary disease (COPD) animal model by repeatedly exposing mice to high concentrations of ozone.

Tags

Chronic Obstructive Pulmonary Disease COPD Ozone Exposure OE Model Mice Underlying Mechanism Screening Of New Drugs Pathological Processes Ozone Concentration Perspex Box Air Vent Pipe Ozone Probe Micro-computed Tomography Lung Fatigue Treadmill Running Distance Running Time
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