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Journal / Genetics / 激光 Microirradiation 研究体内细胞对简单复杂 DNA…
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Genetics

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激光 Microirradiation 研究体内细胞对简单复杂 DNA 损伤的反应
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激光 Microirradiation 研究体内细胞对简单复杂 DNA 损伤的反应

Article DOI: 10.3791/56213-v • 10:44 min • January 31st, 2018
January 31st, 2018 •
*1, *2, 2, 2, 2, 2,3,4, 1
1Department of Biological Chemistry, School of Medicine, University of California, Irvine, 2Beckman Laser Institute and Medical Clinic, University of California, Irvine, 3Department of Developmental and Cell Biology, School of Biological Sciences, University of California, Irvine, 4Department of Biomedical Engineering and Surgery, University of California, Irvine
* These authors contributed equally

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该协议的目的是描述如何使用激光 microirradiation 诱导不同类型的 dna 损伤, 包括相对简单的断链和复杂的损害, 研究 dna 损伤信号和修复因子在损伤部位的组装在体内.

Tags

遗传学 问题 131 激光 microirradiation 医学中的激光 dna 损伤 dna 损伤反应 dna 修复 聚 (ADP-核糖) 聚合酶 (PARP) 复合损伤 链断裂 基底损伤
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