Überwachung von Zelle zu Zelle Übertragung von Prion-wie Protein-Aggregate in Drosophila Melanogaster
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10:26 min
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March 12, 2018
DOI:
Summary
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Beweise sammeln, unterstützt die Idee, dass Pathogene Protein-Aggregate im Zusammenhang mit neurodegenerativen Erkrankungen verteilt zwischen den Zellen mit Prion-ähnliche Eigenschaften. Hier beschreiben wir eine Methode, die ermöglicht die Visualisierung von Zelle zu Zelle ausbreiten von Prion-ähnlichen Aggregaten im Modellorganismus Drosophila Melanogaster.
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Donnelly, K. M., Pearce, M. M. P. Monitoring Cell-to-cell Transmission of Prion-like Protein Aggregates in Drosophila Melanogaster. J. Vis. Exp. (133), e56906, doi:10.3791/56906 (2018).
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