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Journal / Immunology and Infection / 人性化的 nod/scid/il2γ空 (hu-nsg) 小鼠 hiv…
JoVE Journal
Immunology and Infection

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JoVE Journal Immunology and Infection
人性化的 nod/scid/il2γ空 (hu-nsg) 小鼠 hiv 复制和延迟研究模型
Killer Artificial Antigen Presenting Cells (KaAPC) for Efficient In Vitro Depletion of Human Antigen-specific T Cells
Journal (Immunology and Infection)
Killer Artificial Antigen Presenting Cells (KaAPC) for Efficient In Vitro Depletion of Human Antigen-specific T Cells
Analysis of Interactions between Endobiotics and Human Gut Microbiota Using In Vitro Bath Fermentation Systems
Journal (Immunology and Infection)
Analysis of Interactions between Endobiotics and Human Gut Microbiota Using In Vitro Bath Fermentation Systems
 
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人性化的 nod/scid/il2γ空 (hu-nsg) 小鼠 hiv 复制和延迟研究模型

Article DOI: 10.3791/58255-v • 07:10 min • January 7th, 2019
January 7th, 2019 •
1, 1, 1,2, 1, 1
1Department of Molecular and Cellular Biology, Beckman Research Institute of City of Hope, 2Irell and Manela Graduate School of Biological Sciences, Beckman Research Institute of City of Hope

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该方案提供了一种方法, 建立人性化小鼠 (hu-nsg) 通过肝内注射人类造血干细胞到辐射条件下的新生儿 nsg 小鼠。hu-nsg 小鼠容易感染 hiv 感染和组合抗逆转录病毒疗法 (cart), 是治疗艾滋病毒复制和潜伏期调查的合适病理生理模型。

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免疫学与感染 第143期 新生儿 nsg 小鼠 人性化小鼠 hsc hiv cat 延迟
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