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Chemistry

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Synthesis of Esters Via a Greener Steglich Esterification in Acetonitrile
 

Synthesis of Esters Via a Greener Steglich Esterification in Acetonitrile

Article DOI: 10.3791/58803-v 06:52 min October 30th, 2018
October 30th, 2018

Kapitel

Summary

A modified Steglich esterification reaction was used to synthesize a small library of ester derivatives with primary and secondary alcohols. The methodology uses a non-halogenated and greener solvent, acetonitrile, and enables product isolation in high yields without the need for chromatographic purification.

Tags

Keywords: Esterification Steglich Esterification Green Chemistry Acetonitrile Carboxylic Acid Alcohol Ester Synthesis Purification Extraction Workup
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