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Murine Model of Metastatic Liver Tumors in the Setting of Ischemia Reperfusion Injury
JoVE Journal
Krebsforschung
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JoVE Journal Krebsforschung
Murine Model of Metastatic Liver Tumors in the Setting of Ischemia Reperfusion Injury
DOI:

00:05 min

August 30, 2019

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Kapitel

  • 00:04Titel
  • 00:50Tumor Cell Injection
  • 02:37Ischemia and Reperfusion Injury
  • 04:27Splenectomy
  • 05:06Results: Representative Micrometastasis Evaluation After Murine Tumor Cell Injection
  • 05:28Conclusion

Summary

Automatische Übersetzung

We describe in detail a clinically relevant colorectal cancer liver metastases (CRLM) tumor model and the influence of liver ischemia reperfusion (I/R) in tumor growth and metastasis. This model can help to better understand the mechanisms underlying surgery-induced promotion of liver metastatic growth.

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