JoVE Journal
Chemistry
Chemistry
Ein Abonnement für JoVE ist erforderlich, um diesen Inhalt ansehen zu können.
Summary
We exposed a microphysiological system (MPS) with intestine and liver organoids to acetaminophen (APAP). This article describes the methods for organoid production and APAP pharmacokinetic and toxicological property assessments in the MPS. It also describes the tissue functionality analyses necessary to validate the results.