Implantation und Steuerung von drahtlosen, batterielosen Systemen für periphere Nervenschnittstellen

9.3K Aufrufe

Zitiert von 4

07:13 Min.

20. Oktober 2021

10.3791/63085-v

20. Oktober 2021

9.3K Aufrufe

Hongkai Wang¹^,² , Dom D’Andrea¹ , Yeon Sik Choi³^,⁴ , Yasmine Bouricha¹ , Grace Wickerson³^,⁴ , Hak-Young Ahn³ , Hexia Guo³^,⁴ , Yonggang Huang³^,⁴^,⁵^,⁶ , Milap S. Sandhu⁷ , Sumanas W. Jordan⁸ , John A. Rogers³^,⁴^,⁶^,⁹^,¹⁰^,¹¹^,¹² , Colin K. Franz¹^,³^,¹³

¹Laboratory of Regenerative Rehabilitation, Shirley Ryan AbilityLab, Department of Physical Medicine and Rehabilitation, Northwestern University Feinberg School of Medicine, ²Northwestern University Interdepartmental Neuroscience Program, ³Center for Bio-integrated Electronics, Querrey Simpson Institute for Bioelectronics, Northwestern University, ⁴Department of Materials Science and Engineering, Northwestern University, ⁵Department of Civil and Environmental Engineering, Northwestern University, ⁶Department of Mechanical Engineering, Northwestern University, ⁷Arms and Hands Lab, Shirley Ryan AbilityLab, Department of Physical Medicine and Rehabilitation, Northwestern University Feinberg School of Medicine, ⁸Division of Plastic and Reconstructive Surgery, Biologics, Shirley Ryan AbilityLab, Northwestern University, ⁹Department of Biomedical Engineering, Northwestern University, ¹⁰Department of Neurological Surgery, Northwestern University, ¹¹Department of Chemistry, Northwestern University, ¹²Department of Electrical and Computer Engineering, Northwestern University, ¹³The Ken and Ruth Davee Department of Neurology, Northwestern University Feinberg School of Medicine

Dabei handelt es sich um ein Protokoll für die chirurgische Implantation und den Betrieb einer drahtlos betriebenen Schnittstelle für periphere Nerven. Wir demonstrieren die Nützlichkeit dieses Ansatzes anhand von Beispielen von Nervenstimulatoren, die entweder auf dem Ischias- oder dem Phrenicusnerv der Ratte platziert wurden.

Weitere Videos entdecken

Peripheres Nervenschnittstellen-Interface

Drahtlose Nervenstimulation

Batterieloses Implantat

Ischiasnervmodell

Phrenikusnervmodell

Elektrische Stimulation

Kombinierte Muskelaktionspotenziale

Nervenregeneration

Induktive Energieübertragung

Elektromyographie-Analyse

Chapters in this video

0:00

Introduction

0:58

Surgical Procedure for Implantation of a Wireless, Battery‐Free Peripheral Nerve Interface on the Right Sciatic Nerve of the Rat for Electrical Stimulation

3:07

Surgical Procedure for the Implantation of Wireless Stimulators on the Left Phrenic Nerve of the Rat

4:46

Wireless Delivery of Therapeutic Electrical Stimulation

5:29

Results: Nerve Conduction Studies, EMG Recording, and Nerve Regeneration in the Sciatic Nerve Injury Model

6:42

Conclusion