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Journal / Chemistry / Synthesis of a Borylated Ibuprofen Derivative…
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Synthesis of a Borylated Ibuprofen Derivative Through Suzuki Cross-Coupling and Alkene Boracarboxylation Reactions

Article DOI: 10.3791/64571-v • 08:56 min • November 30th, 2022
November 30th, 2022 •
*1, *1, 1, 1, 1
1C. Eugene Bennett Department of Chemistry, West Virginia University
* These authors contributed equally

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Summary
Automatic Translation

The present protocol describes a detailed benchtop catalytic method that yields a unique borylated derivative of ibuprofen. 

Tags

Borylated Ibuprofen Derivative Suzuki Cross-Coupling Alkene Boracarboxylation Synthesis Protocol Moderate Yield Conventional Benchtop Chemistry Nitrogen Filled Glove Box Tandem Cross-coupling Copper-catalyzed Work Of Oxylation Alpha-substituted Styrene Derivatives Unsubstituted Styrene Derivatives Aqueous Workup Trace Impurities Recrystallizations 4-isobutylstyrene Synthesis Palladium Tetrakistriphenylphosphine Anhydrous Potassium Carbonate Scintillation Vial Magnetic Stir Bar Argon Purging
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