Johannes Kepler University View Institution's Website 1 article published in JoVE Biology In-vivo Detection of Protein-protein Interactions on Micro-patterned Surfaces Julian Weghuber1, Stefan Sunzenauer1, Mario Brameshuber1, Birgit Plochberger1, Clemens Hesch1, Gerhard J. Schutz1 1Institute of Biophysics, Johannes Kepler Universitat Linz This video shows experiments with subsequent analysis of protein-protein interactions by the use of micro-patterned surfaces. The approach offers the possibility to detect protein interactions in living cells and combines high throughput capabilities with the possibility to extract quantitative information.