G.F. MacDonald Centre for Lung Health 1 article published in JoVE Medicine Assessment of Pulmonary Capillary Blood Volume, Membrane Diffusing Capacity, and Intrapulmonary Arteriovenous Anastomoses During Exercise Vincent Tedjasaputra1,2, Sean van Diepen3, Sophie É Collins1,4, Wade M. Michaelchuk1,2, Michael K. Stickland1,5 1Division of Pulmonary Medicine, University of Alberta, 2Faculty of Physical Education and Recreation, University of Alberta, 3Divisions of Critical Care and Cardiology, University of Alberta, 4Faculty of Rehabilitation Medicine, University of Alberta, 5G.F. MacDonald Centre for Lung Health To assess the pulmonary diffusion and vasculature responses to exercise, we describe the multiple-inspired oxygen diffusion capacity technique to determine capillary blood volume and membrane diffusing capacity, as well as agitated saline contrast echocardiography to assess the recruitment of intrapulmonary arteriovenous anastomoses.