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JoVE Journal

Scientific video journal. Peer-reviewed. Indexed in PubMed and Web of Science.

Publish with JoVE

Editorial Board

Methods Collections

Testimonials

“JoVE helps make experimental techniques more accessible. By seeing methods in action, researchers can better replicate experiments and avoid misinterpretation. It improves reproducibility and saves time in the lab.”

Morven A. Cameron

Researcher

Western Sydney University

“The video brings the research to life and I think that's important for a user community … it is a time-saver in many ways as well.”

Delphine Dean

Author

Clemson University

“The visual medium helps researchers better understand and replicate our methods, especially the crucial steps for preventing experimental artifacts.“

Mansur Zhussupbekov

Researcher

Cornell University

“We've used Jove publications on countless occasions in the lab when implementing new methods and protocols and so when we had the opportunity to publish with Jove, there was no question that this would be a perfect place to share the method we established.“

Blase Rokusak

Researcher

University of Nebraska at Kearney

Why Choose JoVE Journal

Boost Research Productivity

Save time mastering new protocols and efficiently onboarding and training lab members

Optimize Lab Resources

Reduce lab expenses and conserve valuable resources

Advance Your Career

Build essential skills and expand your expertise quickly learning new research technologies

JoVE Journal

Most Recent

In-vivo and Ex-vivo Calcium Imaging of an Olfactory Circuit Neuron in the Third-Instar Drosophila melanogaster Larva

High-throughput Imaging and Analysis Workflow for Evaluating Skin Cell Phenotypes and Proliferation States in Tissue Samples

Detection of Anti-MDA5 Autoantibodies Using HeLa Cells and Immunocytochemistry with Light Microscopy

An Obstructive Chronic Pancreatitis Model Established Through Electrocoagulation

Development of a Neonatal Piglet Acute Lung Injury Model Recreating the Early Environment of Preterm Infant Lungs

Comet Assay to Quantify DNA Damage in FLT3 Mutant-expressing 32D Cells after Exposure to Type I and Type II FLT3 Inhibitors

Microfluidic Chip for Axonal Injury Models Construction and Enabling Multi-Omics Analysis

Inducing Targeted Mild Hyperthermia in Murine Tumor Models through Photothermal Conversion of Near-infrared Light by Intratumoral Gold Nanorods

Cell Subtype-specific Analysis of Neuronal Membrane Proteasome in Somatosensory Neurons

Adapting Taylor Dispersion to Measure the Dispersion Coefficient of Electrolyte Solutions via an Accessible Microfluidic Setup

Most Watched

Agarose Gel Electrophoresis for the Separation of DNA Fragments

Aseptic Laboratory Techniques: Plating Methods

Using Virtual Reality to Transfer Motor Skill Knowledge from One Hand to Another

Hi-C: A Method to Study the Three-dimensional Architecture of Genomes.

Polymerase Chain Reaction: Basic Protocol Plus Troubleshooting and Optimization Strategies

Whole Animal Perfusion Fixation for Rodents

Manual Restraint and Common Compound Administration Routes in Mice and Rats

Electrode Positioning and Montage in Transcranial Direct Current Stimulation

Passaging HuES Human Embryonic Stem Cell-lines with Trypsin.

NanoDrop Microvolume Quantitation of Nucleic Acids

Publications by Nobel Laureates

Light-driven Molecular Motors on Surfaces for Single Molecular Imaging

Preparation, Purification, and Use of Fatty Acid-containing Liposomes

An ELISA Based Binding and Competition Method to Rapidly Determine Ligand-receptor Interactions

A Simple Method for the Size Controlled Synthesis of Stable Oligomeric Clusters of Gold Nanoparticles under Ambient Conditions

An In Vitro Enzymatic Assay to Measure Transcription Inhibition by Gallium(III) and H3 5,10,15-tris(pentafluorophenyl)corroles

High Throughput Screening of Fungal Endoglucanase Activity in Escherichia coli

Biology

An Ex Vivo Explant Model for Studying Glial Interactions in the Mouse Retina

Efficient Techniques for Comprehensive Sampling of Accessible Tissues in Adult Xenopus

Preparation of Intact Tissue for Microscopic Analysis of the Endosperm Cell Layer in Developing and Mature Arabidopsis Seeds

In Vivo Application of TurboID-based Proximity Labeling in Drosophila melanogaster

Non-Viral Engineering of Primary Human T Cells via Homology-Mediated End-Joining Targeted Integration of Large DNA Templates

Application of I TASSER, trRosetta, UCSF Chimera, HADDOCK server, and HEX loria for De Novo and In Silico Design of Proteins

Sexual Crosses with the Mucoromycete Phycomyces blakesleeanus

Incorporating Target Protein Structure Flexibility and Dynamics in Computational Drug Discovery Using Ensemble-Based Docking Analysis

Efficient Generation Human Induced Pluripotent Stem Cells from Human Somatic Cells with Sendai-virus

An in vivo Crosslinking Approach to Isolate Protein Complexes From Drosophila Embryos

Chemistry

Automated Preparation of [68Ga]Ga-3BP-3940 on a Synthesis Module for PET Imaging of the Tumor Microenvironment

Scalable Syntheses of Graphene Oxide and Reduced Graphene Oxide using Cascade Design Oxidation and Highly Basic Reduction Reactions

Fluid-cell Raman Spectroscopy for operando Studies of Reaction and Transport Phenomena during Silicate Glass Corrosion

Flavonoid Content During the Growth and Floral Development of Calendula officinalis L.

Quantitative Structure-Activity Relationship, Activity Prediction, and Molecular Dynamics of Non-nucleotide Reverse Transcriptase Inhibitors

Extraction and Detection of Geosmin and 2-Methylisoborneol in Water and Fish using High-Capacity Sorptive Extraction Probes and GC-MS

Development and Characterization of Fusidic Acid-Loaded Alginate-Aloe vera Based Hydrogel Film

Detection of Regulated Ergot Alkaloids in Food Matrices by Liquid Chromatography-Trapped Ion Mobility Spectrometry-Time-of-Flight Mass Spectrometry

Demonstrating the Simplicity and In Situ Temperature Monitoring of the Mechanochemical Synthesis of Metal Chalcogenides Suitable for Thermoelectrics

Microwave-Assisted Extraction of Phenolic Compounds and Antioxidants for Cosmetic Applications Using Polyol-Based Technology

Immunology and Infection

Murine Nasal Lavage Fluid Collection without Blood Contamination

In Vitro Culture for H5N1-Specific Duck T Cells and Detection of Immune Responses Using Intracellular Cytokine Staining Method

Rapid Detection of Fecal Antigen of Helicobacter pylori Infection Based on Double Antibody Sandwich Detection Technology

Bioreactor Assembly for Continuous Culture of Complex Fecal Communities

Isolation, Fixation and Characterization of Juvenile Gilthead Seabream Head Kidney Leukocytes by Flow Cytometry

Cell-Free Dot Blot as a Practical and Adaptable Immunoassay Platform for the Detection of Antibody Response in Human and Animal Sera

Murine Model of Advanced Periodontitis Induced by Nylon Ligature in the Second Upper Molar

Rapid Detection of Helicobacter pylori Virulence and Typing Using Quantum Dot Labeling Technology

Reprograming Model of Human Monocyte-derived Macrophages for In-vitro Assays

Rapid and Specific Detection of Acinetobacter baumannii Infections Using a Recombinase Polymerase Amplification/Cas12a-based System

Neuroscience

Whole-mount Retinal Organoid Visualization with Cellular Resolution

Fluorescence-Guided Matrix-assisted Laser Desorption/Ionization with Laser-Induced Postionization Mass Spectrometry of Individual Rat Neural Cells

PIPEMAT-RS: Development and Validation of a Standardized MATLAB Pipeline for Resting-State EEG Preprocessing

Studying the Coding Profiles of Somatic Stimulation on Cardiac-locked Neuronal Responses in the Rat Spinal Dorsal Horn

Multiscale Investigations of Cortical Processing by Integrating Laminar Polytrodes and Optogenetics with Micro Electrocorticography in Rodents

Localizing Function-specific Targets for Transcranial Magnetic Stimulation in the Absence of Navigation Equipment

Randomized, Triple-Blind, and Parallel-Controlled Trial of Transcranial Direct Current Stimulation for Cognitive Rehabilitation after Stroke

Neuroimaging-Guided TMS–EEG for Real-Time Cortical Network Mapping

In ovo Expression of MicroRNA in Ventral Chick Midbrain

Testimonials

Morven A. Cameron

Delphine Dean

Mansur Zhussupbekov

Blase Rokusak

Why Choose JoVE Journal

Boost Research Productivity

An In Vitro Enzymatic Assay to Measure Transcription Inhibition by Gallium(III) and H₃ 5,10,15-tris(pentafluorophenyl)corroles

Automated Preparation of [⁶⁸Ga]Ga-3BP-3940 on a Synthesis Module for PET Imaging of the Tumor Microenvironment