Diaphragm Movement

Diaphragm movement is the rhythmic contraction and relaxation of the dome-shaped muscle that drives ventilation, making it central to normal breathing and clinical assessment of respiratory function. During inspiration, the diaphragm contracts and flattens, increasing thoracic volume and lowering intrathoracic pressure so air flows into the lungs; during quiet expiration, it relaxes and returns upward as elastic recoil reduces lung volume. Clinicians evaluate its excursion and coordination with imaging, ultrasound, or physical examination to identify impaired breathing mechanics associated with conditions such as diaphragmatic paralysis, neuromuscular disease, and respiratory failure. These assessments can guide diagnosis, monitoring, and treatment decisions.

Diaphragm Movement - Related Videos

Research

JoVE Journal - Medicine

Diagnostic Ultrasound Imaging of Mouse Diaphragm Function

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Cited by 7 •

2014

Diagnostic ultrasound imaging has proven to be effective in diagnosing various respiratory diseases in human and animal subjects. We demonstrate a comprehensive ultrasound protocol utilized by Dr. Zuo's lab to analyze diaphragm kinetics specifically in mouse models. This is also a non-invasive research technique which can provide quantitative information on mouse respiratory muscle function.

Functional and Morphological Assessment of Diaphragm Innervation by Phrenic Motor Neurons

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Cited by 16 •

2015

Compound muscle action potential recording quantitatively assesses functional diaphragm innervation by phrenic motor neurons. Whole-mount diaphragm immunohistochemistry assesses morphological innervation at individual neuromuscular junctions. The goal of this protocol is to demonstrate how these two powerful methodologies can be used in various rodent models of spinal cord disease.

Fluorescence Imaging of Calcium Dynamics at Neuromuscular Junctions in the Diaphragm of a Transgenic Mouse

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2025

Source: Heredia, D. J., et. al. Ex Vivo Imaging of Cell-specific Calcium Signaling at the Tripartite Synapse of the Mouse Diaphragm. J. Vis. Exp. (2018) This video demonstrates fluorescence imaging of calcium dynamics at neuromuscular junctions (NMJs) in a transgenic mouse expressing genetically encoded calcium indicators. A NJM is identified by fluorescently tagged acetylcholine receptors in the diaphragm with the phrenic nerve. An image splitter is used to visualize multiple signals...

Eye Movement Monitoring of Memory

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Cited by 10 •

2010

Eye movement monitoring (or eye tracking) reveals where in space the eyes linger, when and for how long. Here, we demonstrate how eye tracking can be used to investigate the integrity of memory in multiple participant populations, without requiring verbal, or otherwise explicit, reports.

Education

JoVE Core - Anatomy and Physiology

Anatomical Movements

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2023

Anatomical movements refer to the various actions or motions that can be performed by the body's joints and muscles. These movements are described using specific terms to provide a standardized way of discussing and understanding the range of motion at different joints. Here are some common anatomical movements: Flexion and extension motions are in the sagittal (anterior–posterior) plane of motion. These movements take place at the shoulder, hip, elbow, knee, wrist, metacarpophalangeal,...

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