Surgical Scars

Surgical scars are visible changes in the skin and underlying tissue that form as the body repairs an incision or other operative wound. Healing begins with blood clotting and inflammation, followed by fibroblast activity that deposits collagen and tissue remodeling that gradually changes the scar’s strength, color, and texture. In clinical practice, scar assessment helps distinguish expected healing from complications such as infection, wound separation, hypertrophic scarring, or keloids. Understanding these processes supports surgical planning, patient counseling, and treatments including appropriate wound care, pressure therapy, silicone-based products, injections, laser procedures, and revision surgery.

Surgical Scars - Related Videos

Research

JoVE Journal - Biology

Visualizing Scar Development Using SCAD Assay - An Ex-situ Skin Scarring Assay

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2022

This protocol describes the generation of a skin-fascia explant termed "SCar like tissue in A Dish" or SCAD. This model allows unprecedented visualization of single fibroblasts during scar formation.

Surgical Management of Meatal Stenosis with Meatoplasty

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Cited by 13 •

2010

Meatoplasty, surgical management of meatal stenosis.

Surgical Correction for Pediatric Epiblepharon and Trichiasis

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2025

Here, we present a protocol for surgical correction for pediatric epiblepharon and trichiasis.

A Mouse Model of Mechanotransduction-driven, Human-like Hypertrophic Scarring

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Cited by 3 •

2024

This protocol will explain how to establish a hypertrophic scarring murine model that increases mechanotransduction signaling to simulate human-like scarring. This method involves increasing mechanical tension across a healing incision in a mouse and using a specialized device to create reproducible, excessive scar tissue for detailed histological and bioinformatic analyses.

In Vitro Model of Human Cutaneous Hypertrophic Scarring using Macromolecular Crowding

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Cited by 8 •

2020

This protocol describes the use of macromolecular crowding to create an in vitro human hypertrophic scar tissue model that resembles in vivo conditions. When cultivated in a crowded macromolecular environment, human skin fibroblasts exhibit phenotypes, biochemistry, physiology, and functional characteristics resembling scar tissue.

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