Eyelash Corneal Contact

Eyelash corneal contact occurs when an eyelash touches or becomes trapped against the cornea, the transparent surface at the front of the eye, causing a common ocular foreign-body sensation. Contact stimulates corneal sensory nerves, triggering blinking, reflex tearing, redness, and discomfort; prolonged rubbing or embedded lashes may produce a corneal abrasion. In medicine, assessment distinguishes transient contact from conditions such as trichiasis, in which misdirected eyelashes repeatedly touch the eye. Careful examination and appropriate removal can relieve symptoms and help prevent epithelial injury, while persistent pain, blurred vision, light sensitivity, or redness warrants professional evaluation.

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JoVE Journal - Cancer Research
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Cited by 36 •

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The aqueous humor is a high-yield liquid biopsy for retinoblastoma, intraocular cancer that cannot be biopsied in vivo due to the risk of extraocular spread. Herein, a method for safely extracting aqueous humor via clear corneal paracentesis and steps for genomic analysis to identify prognostic biomarkers are presented.

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JoVE Journal - Medicine
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Corneal Donor Tissue Preparation for Endothelial Keratoplasty

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Cited by 31 •

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Endothelial corneal transplantation is a surgical technique for treatment of posterior corneal diseases. Mechanical microkeratome dissection to prepare tissue results in thinner, more symmetric grafts with less endothelial cell loss and improved outcomes. Dissections can be performed at the eye bank prior to corneal transplantation surgery.

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JoVE Journal - Medicine

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Cited by 30 •

2015

Corneal collagen cross-linking (CXL) is the only conservative treatment currently available to halt keratoconus progression by improving the biomechanical rigidity of the corneal stroma. The aim of this manuscript is to highlight the methods of three different protocols of CXL: conventional CXL (C-CXL), accelerated CXL (A-CXL), and iontophoresis CXL (I-CXL).

Development of an In Vitro Ocular Platform to Test Contact Lenses

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Cited by 14 •

2016

Current in vitro models for evaluating contact lenses (CLs) and other eye-related applications are severely limited. The presented ocular platform simulates physiological tear flow, tear volume, air exposure and mechanical wear. This system is highly versatile and can be applied to various in vitro analyses with CLs.

An Alkali-burn Injury Model of Corneal Neovascularization in the Mouse

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Cited by 75 •

2014

Neovascularization (NV) of the cornea can complicate multiple visual pathologies. Utilizing a controlled, alkali-burn injury model, a quantifiable level of corneal NV can be produced for mechanistic study of corneal NV and evaluation of potential therapies for neovascular disorders.

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