Volume Change Measurement
Volume Change Measurement - Related Videos
01:17
Work Done During Volume Change
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2023
In mechanics, work is done on an object when the force acting on it displaces the object. In thermodynamics, work done on a system can be estimated when the system's volume changes during any thermodynamic process. Consider a gas confined to a cylinder fitted with a movable piston at one end. If the gas expands from volume V1 to volume V2, it exerts a force on the piston, such that the piston moves by a distance dr. The work done by the gas on the piston can be expressed as If p is the...
01:26
Unsoundness of Aggregate due to Volume Change
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2024
Unsoundness in aggregates due to volume changes is primarily caused by the physical alterations aggregates undergo, such as freezing and thawing, thermal changes, and wetting and drying. Unsound aggregates, when subjected to these changes, result in volume change upon disintegration. This, in turn, contributes to the deterioration of concrete, including scaling, pop-outs, and cracking. Particular types of aggregates, such as porous flints, cherts, and those containing clay minerals, are...
02:32
Le Chatelier's Principle: Changing Volume (Pressure)
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2020
For gas-phase equilibria, changes in the concentrations of reactants and products can occur with altered volume and pressure. The partial pressure, P, of an ideal gas is proportional to its molar concentration, M. So changes in the partial pressures of any reactant or product are essentially changes in concentrations; therefore, these changes yield the same effects on equilibria. Aside from adding or removing reactants or products, the pressures (concentrations) of species in a gas-phase...
08:51
Understanding Concentration and Measuring Volumes
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2023
Solutions are utilized to some degree in almost all biological research applications. Therefore understanding how to measure and manipulate them is imperative to any experiment. In this video, concepts in preparing solutions are introduced. Solutions consist of a solute dissolved in solvent to yield a homogeneous mixture of molecular substances. Solutions are generally identified by their components and corresponding concentrations. Concentrated solutions are diluted through various...
09:15
Measuring Pressure Volume Loops in the Mouse
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Cited by 16 •
2016
This manuscript describes a detailed protocol for the collection of pressure-volume data from the mouse.
FAQs
Meaningful comparisons depend on measuring the same body, organ, tissue, or fluid compartment at defined time points. The resulting values show whether volume has increased, decreased, or remained stable over time. This time-based comparison is especially important when monitoring disease progression or treatment response, because a single measurement cannot show the direction or rate of change.
These approaches obtain volume information through different measurable features. Geometric calculations estimate size from medical images, fluid displacement uses the change associated with an object or compartment displacing fluid, and plethysmography detects volume-related changes through measured changes in a body region or compartment. The selected approach depends on what is being assessed and which measurement is feasible.
Small changes may indicate altered fluid balance or early disease progression, even when the overall change appears limited. Reliable measurement therefore matters because imprecise estimates can obscure clinically relevant differences between time points. Tracking these changes can support closer evaluation of edema, blood or lung volume, organ growth, tumor progression, and response to treatment.
A typical workflow identifies the body structure or fluid compartment of interest, obtains a volume estimate at one defined time point, repeats the measurement later, and compares the values. The estimate may come from medical-image geometry, fluid displacement, or plethysmography. Consistent comparison across time allows the result to inform monitoring, diagnosis, or clinical decision-making.
In medicine, this approach can be applied to several clinically important changes, including edema, blood volume, lung volume, organ growth, and tumor progression. It also helps evaluate whether a treatment is producing a measurable response. Because the same measurement principle can be applied across different structures and compartments, its use extends beyond a single disease or organ system.
Comparing successive volume values provides an objective basis for judging whether a condition is changing over time. Increasing volume may be relevant to edema, organ growth, or tumor progression, while changes in blood or lung volume can provide information about those compartments. When measurements are reliable, the results support diagnosis, monitoring, and decisions about treatment response.