Bitter Sensitive Neuron

Bitter-sensitive neurons are sensory nerve cells that detect bitter-tasting chemicals and help organisms identify potentially harmful substances. In the peripheral taste system, bitter compounds activate specialized receptors on these neurons, triggering electrical signals that travel to the central nervous system and can produce innate or learned avoidance behaviors. Studying their molecular receptors, signal transduction pathways, and connections to feeding circuits reveals how sensory information shapes behavior. Research on bitter-sensitive neurons supports investigations of taste coding, appetite regulation, toxin detection, and the neural mechanisms underlying sensory-guided decision-making.

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Research

JoVE Journal - Neuroscience
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Optical Imaging of Neurons in the Crab Stomatogastric Ganglion with Voltage-sensitive Dyes

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Cited by 4 •

2011

Here we present the methodology for fast and high resolution fluorescent voltage-sensitive dye imaging of detailed activity of neurons in the crab stomatogastric ganglion.

Research

JoVE EoE - Neurophysiology

Optical Recording of Neuronal Activity in Brain Slices Stained with a Voltage-Sensitive Dye

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2025

This video demonstrates a procedure for observing changes in neuronal activity in a brain slice stained with a voltage-sensitive dye. The dye reflects changes in the neuron's membrane potential by altering its fluorescence intensity. Through the application of electrical stimuli and advanced imaging techniques, this process enables visual tracking of real-time changes in neuronal membrane potential based on VSD fluorescence.

Voltage-sensitive Dye Recording from Axons, Dendrites and Dendritic Spines of Individual Neurons in Brain Slices

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Cited by 13 •

2012

An imaging technique for monitoring of membrane potential changes with sub-micrometer spatial and sub-millisecond temporal resolution is described. The technique, based on laser excitation of voltage-sensitive dyes, allows measurements of signals in axons and axon collaterals, terminal dendritic branches, and individual dendritic spines.

Stochastic Noise Application for the Assessment of Medial Vestibular Nucleus Neuron Sensitivity In Vitro

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Cited by 5 •

2019

Galvanic vestibular stimulation in humans exhibits improvements in vestibular function. However, it is unknown how these effects occur. Here, we describe how to apply sinusoidal and stochastic electrical noise and evaluate appropriate stimulus amplitudes in individual medial vestibular nucleus neurons in the C57BL/6 mouse.

Education

JoVE Science Education - Chemistry

Dye-sensitized Solar Cells

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2023

Source: Tamara M. Powers, Department of Chemistry, Texas A&M University Today's modern world requires the use of a large amount of energy. While we harness energy from fossil fuels such as coal and oil, these sources are nonrenewable and thus the supply is limited. To maintain our global lifestyle, we must extract energy from renewable sources. The most promising renewable source, in terms of abundance, is the sun, which provides us with more than enough solar energy to fully fuel our...

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