Waiting
Procesando inicio de sesión ...

Trial ends in Request Full Access Tell Your Colleague About Jove
Journal / Environment / Fabrication of Anisotropic Polymeric Artificial…
JoVE Journal
Environment

Se requiere una suscripción a JoVE para ver este contenido.

JoVE Journal Environment
Fabrication of Anisotropic Polymeric Artificial Antigen Presenting Cells for CD8+ T Cell Activation
Functionalization and Dispersion of Carbon Nanomaterials Using an Environmentally Friendly Ultrasonicated Ozonolysis Process
Journal (Environment)
Functionalization and Dispersion of Carbon Nanomaterials Using an Environmentally Friendly Ultrasonicated Ozonolysis Process
Composition and Properties of Aquafaba: Water Recovered from Commercially Canned Chickpeas
Journal (Environment)
Composition and Properties of Aquafaba: Water Recovered from Commercially Canned Chickpeas
 

Fabrication of Anisotropic Polymeric Artificial Antigen Presenting Cells for CD8+ T Cell Activation

Article DOI: 10.3791/58332-v • 10:16 min • October 12th, 2018
October 12th, 2018 •
*1, *1, 1, 2
1Biomedical Engineering, Translational Tissue Engineering Center, Institute for Nanobiotechnology, Johns Hopkins University School of Medicine, 2Biomedical Engineering, Translational Tissue Engineering Center, Institute for Nanobiotechnology, Ophthalmology, Oncology, Neurosurgery, Materials Science and Engineering, Chemical and Biomolecular Engineering, and the Bloomberg-Kimmel Institute for Cancer Immunotherapy, Johns Hopkins University School of Medicine
* These authors contributed equally

Capítulos

Resumen
Automatic Translation

Here, we present a protocol to quickly and reproducibly generate biologically inspired, biodegradable articifical antigen presenting cells (aAPC) with tunable size, shape, and surface protein presentation for T cell expansion ex vivo or in vivo.

Tags

Anisotropic Polymeric Artificial Antigen Presenting Cells CD8+ T Cell Activation Amino-engineering Particle Physical Properties Biomaterial Immune Cell Interactions Activation Size And Shape Control Biomimetic Particles Cancer Therapy In Vivo Cell Mediated Immune Responses Infectious Disease Type One Diabetes Micro-particle Synthesis Poly(lactic-co-glycolic Acid) PLGA Dichloromethane Polyvinyl Alcohol PVA Solution
Read Article

Get cutting-edge science videos from JoVE sent straight to your inbox every month.

Waiting X
Simple Hit Counter