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Journal / Cancer Research / In Vitro Tumor Zelle Rechallenge für…
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Cancer Research

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JoVE Journal Cancer Research
In Vitro Tumor Zelle Rechallenge für vorausschauende Bewertung der Chimeric Antigen-Rezeptor-T-Zell-Antitumor-Funktion
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In Vitro Tumor Zelle Rechallenge für vorausschauende Bewertung der Chimeric Antigen-Rezeptor-T-Zell-Antitumor-Funktion

Article DOI: 10.3791/59275-v • 08:04 min • February 27th, 2019
February 27th, 2019 •
1,2, 1, 1, 1, *1, *1
1Department of Hematology & Hematopoietic Cell Transplantation, T Cell Therapeutics Research Laboratory, City of Hope Beckman Research Institute and Medical Center, 2Irell and Manella Graduate School of Biological Sciences, City of Hope Beckman Research Institute and Medical Center
* These authors contributed equally

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Hier beschreiben wir eine in-vitro-Kokultur Methode rekursiv Herausforderung Tumor gezielt T-Zellen, die phänotypische und funktionelle Analyse der Antitumor-T-Zell-Aktivität ermöglicht.

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Cancer Research Ausgabe 144 Immuntherapie Adoptiv Zelltransfer Kokulturen Assay Effektor Potenz langfristige Funktion T-Zell-Erschöpfung
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