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Prediciendo en Vivo cargas entrega usando una Barrera Blood-brain Tumor en un plato
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Prediciendo en Vivo cargas entrega usando una Barrera Blood-brain Tumor en un plato

Article DOI: 10.3791/59384-v • 13:34 min • April 16th, 2019
April 16th, 2019 •
1, 1,2, 1,3
1Research Programs Unit, Translational Cancer Medicine Research Program, University of Helsinki, 2Wihuri Research Institute, Biomedicum Helsinki, University of Helsinki, 3Laboratory Animal Center, Helsinki Institute of Life Science (HiLIFE), University of Helsinki

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Medicamentos dirigidos a tumores del sistema nervioso central es un gran desafío. Aquí se describe un protocolo para producir a un imitador in vitro de la tumor-barrera blood-brain con células murinas y humanas y discutir su pertinencia para la previsibilidad del sistema nervioso central tumor targeting in vivo.

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La investigación del cáncer número 146 Barrera Blood-brain tumor glioblastoma transporte intercelular la proyección de imagen in vivo nanopartículas permeabilidad endotelial péptido CooP tumor targeting co-cultivos astrocitos diferenciación de la célula endotelial
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