Waiting
Procesando inicio de sesión ...

Trial ends in Request Full Access Tell Your Colleague About Jove
Journal / Developmental Biology / Transuterine Fetal Tracheal Occlusion Model in…
JoVE Journal
Developmental Biology

Se requiere una suscripción a JoVE para ver este contenido. Inicie sesión o comience su prueba gratuita.

JoVE Journal Developmental Biology
Transuterine Fetal Tracheal Occlusion Model in Mice
Optimization of Renal Organoid and Organotypic Culture for Vascularization, Extended Development, and Improved Microscopy Imaging
Journal (Developmental Biology)
Optimization of Renal Organoid and Organotypic Culture for Vascularization, Extended Development, and Improved Microscopy Imaging
Stimulation of Notch Signaling in Mouse Osteoclast Precursors
Journal (Developmental Biology)
Stimulation of Notch Signaling in Mouse Osteoclast Precursors
 

Transuterine Fetal Tracheal Occlusion Model in Mice

Article DOI: 10.3791/61772-v • 06:31 min • February 5th, 2021
February 5th, 2021 •
1,2, 3, 1, 1, 3, 1
1The Center for Fetal, Cellular & Molecular Therapy, Cincinnati Fetal Center, Division of Pediatric General and Thoracic Surgery, Cincinnati Children’s Hospital Medical Center, 2Department of Pediatric Surgery, Tekirdag Namik Kemal University School of Medicine, 3The Division of Critical Care Medicine, Department of Pediatrics, Cincinnati Children’s Hospital Medical Center

Capítulos

Resumen
Automatic Translation

Various animal models of congenital diaphragmatic hernia and fetal tracheal occlusion present advantages and disadvantages regarding ethical issues, cost, surgical difficulty, size, survival rates, and availability of genetic tools. This model provides a new tool to study the impact of both tracheal occlusion and increased luminal pressure on lung development.

Tags

Transuterine Fetal Tracheal Occlusion Model Mice Technique Advantages Reversibility Cost Reduction Shorter Pregnancy Period Animal Mortality Reduction Wider Opportunities For Genetic Workup Pathophysiology Investigation Congenital Diaphragmatic Hernia Lung Diseases Cows Pulmonary Hypoplasia Mating Vaginal Plug Observation E0 Determination Weight Recording Surgery At E16.5 Instrument Sterilization Surgery Preparation Recovery Environment Abdominal Surface Cleaning Laparotomy Uterine Horns Identification
Read Article

Get cutting-edge science videos from JoVE sent straight to your inbox every month.

Waiting X
Simple Hit Counter