Implantación y control de sistemas inalámbricos sin batería para la interfaz de nervios periféricos

9.3K visualizaciones

Citado por 4

07:13 min.

20 de octubre de 2021

10.3791/63085-v

20 de octubre de 2021

9.3K visualizaciones

Hongkai Wang¹^,² , Dom D’Andrea¹ , Yeon Sik Choi³^,⁴ , Yasmine Bouricha¹ , Grace Wickerson³^,⁴ , Hak-Young Ahn³ , Hexia Guo³^,⁴ , Yonggang Huang³^,⁴^,⁵^,⁶ , Milap S. Sandhu⁷ , Sumanas W. Jordan⁸ , John A. Rogers³^,⁴^,⁶^,⁹^,¹⁰^,¹¹^,¹² , Colin K. Franz¹^,³^,¹³

¹Laboratory of Regenerative Rehabilitation, Shirley Ryan AbilityLab, Department of Physical Medicine and Rehabilitation, Northwestern University Feinberg School of Medicine, ²Northwestern University Interdepartmental Neuroscience Program, ³Center for Bio-integrated Electronics, Querrey Simpson Institute for Bioelectronics, Northwestern University, ⁴Department of Materials Science and Engineering, Northwestern University, ⁵Department of Civil and Environmental Engineering, Northwestern University, ⁶Department of Mechanical Engineering, Northwestern University, ⁷Arms and Hands Lab, Shirley Ryan AbilityLab, Department of Physical Medicine and Rehabilitation, Northwestern University Feinberg School of Medicine, ⁸Division of Plastic and Reconstructive Surgery, Biologics, Shirley Ryan AbilityLab, Northwestern University, ⁹Department of Biomedical Engineering, Northwestern University, ¹⁰Department of Neurological Surgery, Northwestern University, ¹¹Department of Chemistry, Northwestern University, ¹²Department of Electrical and Computer Engineering, Northwestern University, ¹³The Ken and Ruth Davee Department of Neurology, Northwestern University Feinberg School of Medicine

Se trata de un protocolo para la implantación quirúrgica y el funcionamiento de una interfaz alimentada de forma inalámbrica para los nervios periféricos. Demostramos la utilidad de este enfoque con ejemplos de estimuladores nerviosos colocados en el nervio ciático o frénico de rata.

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Interfaz de nervio periférico

estimulación nerviosa inalámbrica

implante sin batería

modelo del nervio ciático

modelo del nervio frénico

estimulación eléctrica

potenciales de acción musculares compuestos

regeneración nerviosa

transferencia de energía inductiva

análisis de electromiografía

Chapters in this video

0:00

Introduction

0:58

Surgical Procedure for Implantation of a Wireless, Battery‐Free Peripheral Nerve Interface on the Right Sciatic Nerve of the Rat for Electrical Stimulation

3:07

Surgical Procedure for the Implantation of Wireless Stimulators on the Left Phrenic Nerve of the Rat

4:46

Wireless Delivery of Therapeutic Electrical Stimulation

5:29

Results: Nerve Conduction Studies, EMG Recording, and Nerve Regeneration in the Sciatic Nerve Injury Model

6:42

Conclusion