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JoVE Journal Engineering
Imaging of the Microstructural Failure Mechanism in the Human Hip
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Imaging of the Microstructural Failure Mechanism in the Human Hip

Article DOI: 10.3791/64947-v • 08:43 min • September 29th, 2023
September 29th, 2023 •
1,2, 2
1School of Mechanical, Medical and Process Engineering, Queensland University of Technology, 2Medical Device Research Institute, College of Science and Engineering, Flinders University

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The protocol enables the measurement of the deformation of the bone microstructure in the entire proximal human femur and its toughness by combining large-volume micro-CT scanning, a custom-made compressive stage, and advanced image processing tools.

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Imaging Microstructural Failure Mechanism Human Hip Bone Microstructure Progressively Increasing Loads Microstructural Failure Behavior Protocol Three-dimensional Microstructural Images Proximal Femur Deformation Clinically Relevant Fractures Femoral Neck Radio-transparent Compressive Stage Micro-computed Tomography (micro-CT) Field Of View Isotropic Pixel Size Force Increment Finite-element Predictions Compression Stage Displacement Prescribed Force Increments Sub-capital Fractures Opening And Shear Femoral Neck Instability Bone Strain Energy Absorption Capacity Cortex Instability Subchondral Bone
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