JOVE JOURNAL

Genetics

Showing 1 - 12 in 452 videos.

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Journal (Genetics)

CRISPR Epigenome Editing in Human Cells using Plasmid DNA Transfection and mRNA Nucleofection Delivery

Anna E. Christenson*¹, Nikita S. Divekar*¹, Mitzi G. Hernández Zamora¹, Carolyn D. Nguyen¹, James K. Nuñez^1,2

¹Department of Molecular and Cell Biology,University of California, Berkeley ²Chan Zuckerberg Biohub - San Francisco

Journal (Genetics)

Single Nucleotide Polymorphism-sensitive FISH Detection of Locus-specific Ribosomal RNA Transcription in Drosophila melanogaster

Jackson Chen¹, Jonathan O. Nelson¹

¹Department of Biochemistry and Cell Biology,Stony Brook University

Journal (Genetics)

Novel And Efficient Method for Drosophila Heart Fluorescence Staining with Cryosectioning

John Watson¹, Sachin Budhathoki¹, Girish C. Melkani^1,2

¹Department of Pathology, Division of Molecular and Cellular Pathology, Heersink School of Medicine,The University of Alabama at Birmingham ²UAB Nathan Shock Center,The University of Alabama at Birmingham

Journal (Genetics)

Genome Editing in the Yellow Fever Mosquito Aedes aegypti using CRISPR-Cas9

Iliano V. Coutinho-Abreu*¹, Fangying Chen*¹, Hsing-Han Li*¹, Noah H. Rose², Omar S. Akbari¹

¹School of Biological Sciences, Section of Cell and Developmental Biology,University of California, San Diego ²School of Biological Sciences, Department of Ecology, Behavior, and Evolution,University of California, San Diego

Journal (Genetics)

In Vivo Monitoring of Transcriptional Activity During Metabolic Transition Using a Bioluminescent Reporter in Yeast

Felipe Muñoz-Guzmán^1,2,3, Pablo Quintrel^1,2, José Benavides-Parra^1,2, Catalina Muñoz-Tapia^2,3,4, Luis F. Larrondo^2,4, Francisco A. Cubillos^1,2,5

¹Facultad de Química y Biología, Departamento de Biología,Universidad de Santiago de Chile ²ANID-Millennium Science Initiative-Millennium Institute for Integrative Biology (iBio)³Centro Científico y Tecnológico de Excelencia Ciencia & Vida, Fundación Ciencia & Vida ⁴Facultad de Ciencias Biológicas,Pontificia Universidad Católica de Chile ⁵ANID-Millennium Nucleus of Patagonian Limit of Life (LiLi)

Journal (Genetics)

Fluorescence Labeling to Visualize Low-Expressed Proteins in Zebrafish

Xuepu Jin*¹, Binghuang Zhang*¹, Yu Sun*¹, Yahan Duan¹, Junchen Lu¹, Jiannan Liu², Jiahuai Han^1,3,4, Yingying Zhang¹

¹State Key Laboratory of Cellular Stress Biology, School of Life Sciences, Faculty of Medicine and Life Sciences,Xiamen University ²Technology Center,Shanxi Xinghuacun Fenjiu Distillery Co., Ltd.³Research Unit of Cellular Stress of CAMS, Cancer Research Center of Xiamen University, Xiang'an Hospital of Xiamen University, School of Medicine,Xiamen University ⁴Laboratory Animal Center,Xiamen University

Journal (Genetics)

Identification of Functionally-Relevant Lentivirus Integration Sites in an Insertional Mutagenesis Cell Library

Dongyang Xu¹, Lu Tang¹, Philipp Kapranov²

¹Institute of Genomics, School of Medicine,Huaqiao University ²State Key Laboratory of Cellular Stress Biology, School of Life Sciences,Xiamen University

Journal (Genetics)

Introductory Analysis and Validation of CUT&RUN Sequencing Data

Junwoo Lee¹, Biji Chatterjee^1,2, Nakyung Oh¹, Dhurjhoti Saha¹, Yue Lu¹, Blaine Bartholomew¹, Charles A. Ishak^1,3

¹Department of Epigenetics and Molecular Carcinogenesis,University of Texas MD Anderson Cancer Center ²Department of Genomic Medicine,University of Texas MD Anderson Cancer Center ³Department of Gynecologic Oncology and Reproductive Medicine,University of Texas MD Anderson Cancer Center

Journal (Genetics)

CIRCLE-Seq for Interrogation of Off-Target Gene Editing

Jeffrey Inen^1,2, Chann Makara Han^1,2, David M. Farrel³, Ganna Bilousova^1,2, Igor Kogut^1,2

¹Department of Dermatology,University of Colorado School of Medicine, Anschutz Medical Campus ²Gates Institute,University of Colorado School of Medicine, Anschutz Medical Campus ³Department of Biochemistry and Molecular Genetics,University of Colorado School of Medicine, Anschutz Medical Campus

Journal (Genetics)

Application of DNA Barcoding to Identify Medicinal Plants

Shuai Yang^1,2, Shilin Chen^1,2, Jing Mo², Junfei Liu², Qi Pan², Chi Song^2,3

¹School of Pharmacy,Guizhou University of Traditional Chinese Medicine ²School of Pharmacy/School of Modern Chinese Medicine Industry,Chengdu University of Traditional Chinese Medicine ³Institute of Herbgenomics,Chengdu University of Traditional Chinese Medicine

Journal (Genetics)

Application of Unsupervised Multi-Omic Factor Analysis to Uncover Patterns of Variation and Molecular Processes Linked to Cardiovascular Disease

Corinna Losert^1,2, Kami Pekayvaz^3,4, Viktoria Knottenberg^3,4, Leo Nicolai^3,4, Konstantin Stark^3,4, Matthias Heinig^1,2,4

¹Institute of Computational Biology, German Research Center for Environmental Health,Helmholtz Zentrum München ²Department of Computer Science, TUM School of Computation, Information and Technology,Technical University of Munich ³Medizinische Klinik und Poliklinik I University Hospital Ludwig-Maximilian University ⁴German Centre for Cardiovascular Research (DZHK), partner site Munich Heart Alliance

Journal (Genetics)

Electrophoretic Analysis of Replication Through Structure-Prone DNA Repeats Within the SV40-Based Human Episome

Nicholas H. Mandel¹, Sergei M. Mirkin¹

¹Department of Biology,Tufts University

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