Particle Number Concentration
Particle Number Concentration - Related Videos
02:41
Concentration and Purification of Viral Particles
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2026
Source: Fricano-Kugler, C. J., et al. Designing, Packaging, and Delivery of High Titer CRISPR Retro and Lentiviruses via Stereotaxic Injection. J. Vis. Exp. (2016).This video demonstrates the step-by-step process for concentrating and purifying lentiviral particles from a mixed suspension containing host cell debris. The procedure utilizes centrifugation, filtration, and PEG-salt precipitation to isolate viral particles while removing soluble impurities. The final product is resuspended in a...
08:43
Pneumatically Driven Microfluidic Platform for Micro-Particle Concentration
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Cited by 3 •
2022
The present protocol describes a pneumatic microfluidic platform that can be used for efficient microparticle concentration.
09:49
Solutions and Concentrations
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2023
Source: Laboratory of Dr. Michael Evans — Georgia Institute of Technology A solution is a homogeneous mixture containing some components in small amounts, called solutes, and one component in a large amount, called the solvent. Solid-liquid solutions contain one or more solid solutes dissolved in a liquid solvent. Solutions are ubiquitous in chemistry: they are used to store and handle small amounts of material, carry out chemical reactions, and develop materials with controllable properties.
09:41
Concentration Dependence - Student Protocol
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2020
Source: Smaa Koraym at Johns Hopkins University, MD, USA Concentration DependenceExpand In this experiment, you will combine varying concentrations of aqueous HCl and sodium thiosulfate to make solid sulfur, which rapidly gathers into opaque yellow particles at a certain sulfur concentration. Since the reaction solution starts clear and colorless, you can easily tell when it reaches that concentration. You'll use the same test tube and total volume each time, so it will take the same amount...
05:07
Development of a Nose-only Inhalation Toxicity Test Chamber That Provides Four Exposure Concentrations of Nano-sized Particles
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Cited by 2 •
2019
A nose-only inhalation toxicity chamber capable of testing inhalation toxicity at four different exposure concentrations was designed and validated for flow field uniformity and cross-contamination between the exposure ports for each concentration. Here, we present a protocol to confirm that the designed chamber is effective for inhalation toxicity testing.
FAQs
Optical particle counters detect individual particles through light scattering, while condensation particle counters first enlarge particles by condensation so they can be counted. Both approaches rely on sampling a known volume and recording discrete particles rather than estimating total material mass. The instrument choice therefore affects how engineers observe particle populations in a gas or liquid measurement context.
Mass measurements describe the amount of material contributed by particles, whereas particle number concentration indicates how many discrete particles are present. These measures can change differently when particle populations shift in size or abundance. Using both helps engineers identify changes in particle size distributions and evaluate aerosol behavior more completely than either measurement alone.
Measurements taken at relevant points in an engineered system can show whether particle abundance changes as particles move through that system. Such changes provide evidence about transport behavior and can help relate particle movement to emissions, ventilation, or filtration performance. Interpreting concentration together with particle size distribution gives engineers a more informative view of process behavior.
Light-scattering instruments count particles through the optical signal produced during detection. Condensation-based instruments instead grow particles before counting them, using the enlarged particles to support detection. The two mechanisms represent different measurement pathways for the same overall objective, so engineers select or compare them according to the particle-counting context being investigated.
The measurement begins by sampling a defined volume of gas or liquid. An instrument then detects and counts particles individually, using either light scattering or condensation growth, depending on the instrument type. Relating the particle count to the sampled volume produces the concentration value, which can then be compared across locations, operating conditions, or engineering tests.
Engineering applications include aerosol characterization, air-quality monitoring, cleanroom validation, filtration testing, and contamination control. In these settings, the measurement helps assess particle abundance under defined conditions and supports comparisons between system states. It can also contribute to evaluations of emissions, ventilation and filtration systems, exposure, and process performance.