Synthetic Prosthesis
Synthetic Prosthesis - Related Videos
07:28
Synthetic Biology
0 Views •
2023
This video presents synthetic biology and its role in bioengineering. Synthetic biology refers to the methods used to genetically modify organisms in order to make them capable of producing large quantities of a product. This product could be a protein that the cell already makes or a new protein that has been encoded in a newly-inserted DNA sequence. Here, we discuss how an organism's genetic material is modified using transformation or transfection. Then, the process is shown in the...
08:08
Oscillation and Reaction Board Techniques for Estimating Inertial Properties of a Below-knee Prosthesis
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Cited by 35 •
2014
Body segmental inertial properties are required for inverse dynamics modeling. Using an oscillation and reaction board technique, inertial properties of below-knee prostheses were measured. Using direct measures of prosthesis inertia in the inverse dynamics model of the prosthetic leg resulted in lower magnitudes of resultant joint forces and moments.
08:46
A Standardized Method for Measuring Internal Lung Surface Area via Mouse Pneumonectomy and Prosthesis Implantation
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Cited by 22 •
2017
Internal lung surface area (ISA) is a critical criterion for assessing lung morphology and physiology in lung diseases and injury-induced alveolar regeneration. We describe here a standardized method that can minimize the measurement bias for ISA in both lung pneumonectomy and prosthesis implantation mouse models.
11:16
Engineering Platform and Experimental Protocol for Design and Evaluation of a Neurally-controlled Powered Transfemoral Prosthesis
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Cited by 15 •
2014
Neural-machine interfaces (NMI) have been developed to identify the user's locomotion mode. These NMIs are potentially useful for neural control of powered artificial legs, but have not been fully demonstrated. This paper presented (1) our designed engineering platform for easy implementation and development of neural control for powered lower limb prostheses and (2) an experimental setup and protocol in a laboratory environment to evaluate neurally-controlled artificial legs on patients with...
04:36
Production of Synthetic Nuclear Melt Glass
0 Views •
Cited by 1 •
2016
A protocol for the production of synthetic nuclear melt glass, similar to trinitite, is presented.
FAQs
Material selection determines whether the device can tolerate the mechanical demands of the anatomy it serves. Polymers, metals, and composites offer engineered options for transmitting forces between the prosthesis and surrounding tissues. Choosing among them requires balancing functional demands with biocompatibility and durability, because material performance influences both short-term operation and long-term suitability.
A prosthesis must fit the affected anatomy closely enough to transmit forces appropriately between the device and surrounding tissues. If its design does not match those mechanical demands, function and mobility may not be restored as intended. Fit therefore works together with material choice and structural design, rather than acting as an independent consideration.
Biocompatibility addresses how well the engineered device can function in contact with the body. It is considered alongside durability, fit, and integration because a prosthesis must remain suitable within its anatomical setting while performing its intended role. Attention to these factors helps reduce complications and supports more reliable long-term performance.
Design begins with the mechanical demands of the missing, damaged, or surgically treated body part. Engineers and clinicians must then consider an appropriate material, anatomical fit, force transmission, durability, biocompatibility, and integration with surrounding tissues. Together, these criteria guide a device toward restoring function, mobility, or appearance while reducing the likelihood of complications.
Medical applications span several anatomical needs. Artificial limbs can support mobility after loss of a limb, joint replacements can substitute for affected joints, and vascular grafts can serve vascular repair or replacement needs. Other implants address additional surgical or disease-related requirements. The specific application determines the mechanical demands and design priorities placed on the device.
Depending on its application, the device may help restore function, improve mobility, or support appearance after injury, disease, or surgery. Its success depends on how well the design matches the affected anatomy and how effectively it integrates with the body. Evaluating durability, fit, biocompatibility, and complications helps assess expected long-term performance and quality-of-life benefits.