Ventricular Morphology
Ventricular Morphology - Related Videos
12:09
Patient-specific Modeling of the Heart: Estimation of Ventricular Fiber Orientations
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Cited by 14 •
2013
A methodology to estimate ventricular fiber orientations from in vivo images of patient heart geometries for personalized modeling is described. Validation of the methodology performed using normal and failing canine hearts demonstrate that that there are no significant differences between estimated and acquired fiber orientations at a clinically observable level.
10:22
Echocardiographic and Histological Examination of Cardiac Morphology in the Mouse
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Cited by 29 •
2017
Echocardiographic examination is frequently used in mice. Expensive high-resolution ultrasound devices have been developed for this purpose. This protocol describes an affordable echocardiographic procedure combined with histological morphometric analyses to determine cardiac morphology.
08:49
Use of Two Intracorporeal Ventricular Assist Devices As a Total Artificial Heart
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Cited by 4 •
2018
Here, we present a protocol using two centrifugal pumps as a total artificial heart replacement.
09:22
Chronic Thromboembolic Pulmonary Hypertension and Assessment of Right Ventricular Function in the Piglet
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Cited by 22 •
2015
Chronic Thromboembolic Pulmonary Hypertension (CTEPH) and Right Ventricular (RV) dysfunction were induced in piglets by progressive obstruction of the pulmonary arteries. Consequences were remarkably similar to those observed in CTEPH patients. This animal model would be a very useful tool for pathophysiology and therapeutic experiments on CTEPH and RV failure.
11:33
Isolation and Kv Channel Recordings in Murine Atrial and Ventricular Cardiomyocytes
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Cited by 15 •
2013
Kv channel dysfunction is associated with cardiac arrhythmias. In order to study the molecular mechanisms that lead to such arrhythmias we utilize a systematic protocol for isolation of atrial and ventricular cardiomyocytes from Kv channel ancillary subunit knockout mice. Isolated cardiomyocytes can then immediately be used for cellular electrophysiological studies, biochemical or immunofluorescence (IF) assays.
FAQs
Size and wall thickness provide complementary structural information about a ventricle. Evaluating them together helps relate chamber geometry to myocardial structure and to changes associated with pressure or volume conditions. This combined assessment can provide more useful context for recognizing ventricular remodeling and cardiomyopathies than either feature considered in isolation.
The ventricles must be assessed in relation to one another and to the great vessels, not only as separate chambers. These spatial relationships provide anatomical context for understanding how the ventricles connect within the heart. Abnormal connections or arrangements may therefore support recognition and characterization of congenital heart defects.
Internal architecture, including the pattern of ventricular trabeculation, adds structural detail beyond overall chamber size and shape. These observations help describe myocardial organization and may contribute to the assessment of cardiomyopathies or congenital abnormalities. Imaging that resolves these features can strengthen the structural basis for diagnosis and clinical interpretation.
Assessment combines anatomical examination with cardiac imaging. Echocardiography, cardiac magnetic resonance, and computed tomography can characterize ventricular geometry, myocardial thickness, trabeculation, and connections with the great vessels. Using these approaches allows clinicians to examine structural features in detail and relate observed abnormalities to cardiac disease or altered ventricular form.
Ventricular morphology is particularly relevant when clinicians evaluate congenital heart defects, cardiomyopathies, or remodeling associated with pressure and volume changes. Structural findings help establish diagnostic context, guide treatment planning, and support decisions about surgical repair. They also provide anatomical information that can be followed as disease changes over time.
Repeated assessment of ventricular structure can document changes in chamber geometry, wall thickness, internal architecture, and spatial relationships. Comparing these findings over time provides structural context for ventricular remodeling and ongoing cardiac disease. This information can complement diagnosis and treatment planning by showing whether relevant anatomical features remain stable or change during follow-up.