Mri Guidance
Mri Guidance - Related Videos
08:20
MRI-guided dmPFC-rTMS as a Treatment for Treatment-resistant Major Depressive Disorder
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Cited by 31 •
2015
Here we outline the procedure for MRI-guided repetitive transcranial magnetic stimulation to the dorsomedial prefrontal cortex as an experimental treatment for major depressive disorder.
06:06
Optogenetic Functional MRI
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Cited by 15 •
2016
This protocol describes the steps and data analysis required to successfully perform optogenetic functional magnetic resonance imaging (ofMRI). ofMRI is a novel technique that combines high-field fMRI readout with optogenetic stimulation, allowing for cell type-specific mapping of functional neural circuits and their dynamics across the whole living brain.
10:14
Automated Robotic Dispensing Technique for Surface Guidance and Bioprinting of Cells
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Cited by 9 •
2016
This protocol describes a bioprinting methodology using an automated robotic depositing system that incorporates etched topographical guidance cues with the precision deposition of a cell bearing hydrogel bioink. The printed cells are directly delivered to the etched features and are able to sense and orientate with them.
03:59
MRI-Guided Repetitive Transcranial Magnetic Stimulation to the Dorsomedial Prefrontal Cortex
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2025
Source: Dunlop, K., et al. MRI-guided dmPFC-rTMS as a Treatment for Treatment-resistant Major Depressive Disorder. J. Vis. Exp. (2015)This video demonstrates the procedure for MRI-guided repetitive transcranial magnetic stimulation (rTMS) targeting the dorsomedial prefrontal cortex (dmPFC) to treat depression.
08:52
Convection Enhanced Delivery of Optogenetic Adeno-associated Viral Vector to the Cortex of Rhesus Macaque Under Guidance of Online MRI Images
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Cited by 31 •
2019
Here, we demonstrate magnetic resonance (MR)-guided convection enhanced delivery (CED) of viral vectors into the cortex as an efficient and simplified approach for achieving optogenetic expression across large cortical areas in the macaque brain.
FAQs
Spatial encoding assigns signal information to locations within the imaged subject, allowing anatomy and physiological changes to be represented in their correct positions. During guidance, these images can help relate an intended target to surrounding brain structures and provide visual information for positioning an instrument or treatment. This supports more direct targeting than relying only on indirect anatomical landmarks.
Structural maps show the location and organization of brain anatomy, whereas functional maps connect regions with physiological activity. Using both types of information can help distinguish where a target lies from how that region is functioning. In neuroscience, this combined context is valuable for planning interventions or studies that depend on both anatomical placement and functional relevance.
Near-real-time imaging allows visual information to be updated while a procedure or treatment is being planned, performed, or monitored. This gives investigators a way to compare the intended target with the observed anatomy or physiological changes as the work progresses. The approach can support adjustments based on current images rather than depending entirely on information obtained before the procedure.
A typical use begins by obtaining MRI information for planning and identifying the relevant brain region. The images are then used to guide an instrument, target a region, or track treatment during the procedure. Additional imaging can monitor anatomical or physiological changes afterward or during the intervention, linking the procedural steps with observed outcomes.
MRI guidance can support stereotactic interventions, brain stimulation, biopsy planning, and functional studies. In stereotactic work and biopsy planning, image-based anatomical information helps relate the procedure to a selected brain region. For stimulation and functional studies, structural and functional maps provide context for targeting or interpreting changes associated with the intervention or experimental task.
By linking procedural targeting to structural and functional brain maps, MRI guidance can reduce reliance on indirect landmarks. This may improve correspondence between the intended target and the subject’s observed anatomy, while imaging during or near the procedure can help monitor changes. The same framework also supports noninvasive assessment of outcomes when direct procedural observation is limited.