Stereotactic Device
Stereotactic Device - Related Videos
10:35
Stereotactic Radiosurgery for Gynecologic Cancer
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Cited by 14 •
2012
Stereotactic body radiotherapy (SBRT) involves image-guided, ablative radiation delivered to cancer targets refractory to chemotherapy or to conventional radiation treatment. The robotic-armed Cyberknife SBRT system, using sophisticated target localization, delivers hypofractionated radiation doses capable of sterilizing cancer targets. This article will consider new therapeutic roles of SBRT for gynecological cancers.
05:08
A Stereotactically Guided Ablation Technique for Auditory Cortex Removal in Rats
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2025
This video demonstrates a stereotactically-guided surgical procedure for ablating the auditory cortex in a rat. The steps include identifying anatomical landmarks in an anesthetized rat secured in a stereotactic frame, creating a window on the skull above the auditory cortex, aspirating the cortical layers, and providing post-operative care to assess the impact of the ablation on sound processing.
08:29
Thermal Measurement Techniques in Analytical Microfluidic Devices
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Cited by 6 •
2015
Here, we present three protocols for thermal measurements in microfluidic devices.
07:54
Applying Stereotactic Injection Technique to Study Genetic Effects on Animal Behaviors
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Cited by 15 •
2015
Stereotactic injection of lentiviruses expressing cDNAs or shRNAs can modulate gene expression in specific brain areas of mice. Here, we present a protocol to combine stereotactic injections with behavioral tasks, such as the Open Field Test (OFT) and the Forced Swim Test (FST).
08:17
Dynamic Lung Tumor Tracking for Stereotactic Ablative Body Radiation Therapy
0 Views •
Cited by 9 •
2015
Stereotactic ablative body radiation therapy (SBRT) involves the precise delivery of high-dose radiation to cancer tumor targets. A novel SBRT platform offers a first-of-its-kind gimbaled radiation accelerator mounted within a pivoting O-ring gantry capable of dynamic image-guided tumor tracking. Here, we describe dynamic tumor tracking for lung targets.
FAQs
Targeting combines anatomical landmarks with coordinates derived from imaging to identify a neural structure in three-dimensional space. These reference systems allow the operator to calculate an instrument trajectory rather than rely on visual estimation alone. As a result, injections, recordings, lesions, or other interventions can be directed toward the intended region with greater consistency across procedures.
Rigid frames and frameless guidance systems provide the reference structure needed to translate brain coordinates into an instrument path. A frame physically stabilizes the setup, whereas a frameless system supports image-based spatial guidance without the same fixed frame arrangement. Both approaches are intended to improve positional control and reduce variability during intracranial access.
Trajectory calculation determines how a needle, electrode, probe, or other tool approaches the selected structure. Stabilization helps maintain that path during insertion, reducing unintended movement and limiting disturbance to nearby tissue. Together, these features connect the planned coordinates with controlled tool placement, which is essential when investigators need reproducible access to small or deep neural regions.
Consistent use of imaging coordinates, anatomical reference points, and stabilized insertion paths makes access more reproducible between experiments or subjects. This consistency helps investigators compare injections, recordings, lesions, or stimulation procedures while reducing targeting variability. More reproducible placement also strengthens interpretation of whether observed neural or behavioral outcomes arise from the intended brain region.
A typical workflow identifies the intended brain location from anatomical landmarks and imaging-based coordinates, calculates an appropriate trajectory, and secures the instrument or guidance system before insertion. The selected tool is then advanced along the stabilized path to support the planned injection, recording, lesion, biopsy, or stimulation procedure. The exact workflow depends on the application.
These devices support several forms of controlled intracranial work, including injections, electrophysiological recordings, lesion studies, biopsies, and deep brain stimulation. In research models, they help link a manipulated or measured location with neural-circuit function. In clinical procedures, the same emphasis on spatial control supports interventions that require access to specific brain structures.
By enabling reproducible access to defined neural structures, stereotactic procedures let researchers examine circuit activity, alter selected regions, or evaluate targeted interventions. The resulting measurements or outcomes can be related to a known anatomical location rather than an imprecise insertion site. This makes the approach valuable for studying brain organization and assessing strategies for neurological disease.