Brain Activation Mapping
Brain Activation Mapping - Related Videos
11:15
fMRI Mapping of Brain Activity Associated with the Vocal Production of Consonant and Dissonant Intervals
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2017
The neural correlates of listening to consonant and dissonant intervals have been widely studied, but the neural mechanisms associated with production of consonant and dissonant intervals are less well known. In this article, behavioral tests and fMRI are combined with interval identification and singing tasks to describe these mechanisms.
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Quantitative Susceptibility Mapping of a Human Brain Using Ex-Vivo Magnetic Resonance Imaging
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2025
Quantitative susceptibility mapping, or QSM, quantifies the magnetic susceptibility of brain tissue, which reflects its cellular composition, like myelin content.Begin by acquiring ex-vivo magnetic resonance imaging or MRI data of a fixed human brain hemisphere.Use 3D gradient magnetic fields to magnetize the tissue and collect signals at multiple time points or echoes to reduce background noise and artifacts and enhance the signals.Generate phase maps for all echoes, ensuring the removal of...
02:54
Juxtacellular Recording and Staining for Precise Mapping of Neural Activity in an Awake Rat
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2025
Source: Moore, J. D., et al. Juxtacellular Monitoring and Localization of Single Neurons within Sub-cortical Brain Structures of Alert, Head-restrained Rats. J. Vis. Exp. (2015)This video demonstrates the method of juxtacellular recording and staining in a restrained, awake rat. The procedure involves recording signals from neurons and injecting dye to precisely localize the recording site. This technique allows accurate mapping of neural activity to the brain's anatomical structure.
11:03
Motor Maps
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2023
Source: Laboratories of Jonas T. Kaplan and Sarah I. Gimbel—University of Southern California One principle of brain organization is the topographic mapping of information. Especially in sensory and motor cortices, adjacent regions of the brain tend to represent information from adjacent parts of the body, resulting in maps of the body expressed on the surface of the brain. The primary sensory and motor maps in the brain surround a prominent sulcus known as the central sulcus. The cortex...
10:36
Ultrasound Localization Microscopy for Super-Resolution Mapping of the Rodent Brain Microvasculature
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2025
Ultrasound Localization Microscopy (ULM) is a recently developed technique that allows for an unprecedented level of resolution in imaging the microvasculature in vivo. In this work, we describe in detail how to obtain super-resolved images of the brain microvasculature in rodents using a standardized functional ultrasound imaging platform designed for preclinical research.
FAQs
These signals provide measurable indicators of neural responses in different brain regions. Researchers record changes while a person rests or completes a cognitive, emotional, or sensory task, then visualize the resulting regional patterns. Comparing these signals across conditions helps relate brain activity to specific psychological processes such as attention, memory, perception, decision-making, or emotion.
Task comparisons help identify activity patterns associated with particular mental processes rather than examining one brain state in isolation. A researcher might contrast responses during different cognitive, emotional, or sensory activities, or compare task-related activity with rest. The resulting differences can clarify how brain responses vary with the psychological demands of each condition.
Comparisons across groups can show whether brain-response patterns differ with development, disorders, or treatment. The maps do not simply describe one individual’s neural activity; they also support examination of broader patterns associated with psychological or clinical categories. In this way, activation findings can contribute to research connecting measurable brain responses with theories of behavior and mental processes.
A study typically selects a psychological question, records a neural-response signal while participants rest or perform a specified task, and visualizes changes across brain regions. Researchers then compare the resulting maps across tasks or groups. This workflow produces patterns that can be interpreted in relation to cognitive, emotional, sensory, behavioral, developmental, or treatment-related questions.
It is useful when researchers want to examine how brain responses relate to attention, memory, perception, decision-making, or emotion. The approach can support studies of ordinary psychological processes as well as patterns associated with development, disorders, or treatment. Its value comes from examining measurable neural changes alongside theories about cognition and behavior.
Researchers can compare activation patterns across groups or examine differences before and after treatment-related conditions, when those comparisons are part of the study design. Such analyses may reveal patterns associated with disorders or treatment and connect them to psychological functioning. The maps therefore provide a neural perspective that complements investigation of behavior and mental processes.