Waiting
Traitement de la connexion…

Trial ends in Request Full Access Tell Your Colleague About Jove
Journal / Medicine / Vascular Balloon Injury and Intraluminal…
JoVE Journal
Medicine

Un abonnement à JoVE est nécessaire pour afficher ce contenu.

JoVE Journal Medicine
Vascular Balloon Injury and Intraluminal Administration in Rat Carotid Artery
Internal Jugular Vein Identification and Catheter Exit Site Preparation (Video) | JoVE
Journal (Medicine)
Internal Jugular Vein Identification and Catheter Exit Site Preparation (Video) | JoVE
ECG-Blood Speckle Image Acquisition of Newborns (Video) | JoVE
Journal (Medicine)
ECG-Blood Speckle Image Acquisition of Newborns (Video) | JoVE
 

Vascular Balloon Injury and Intraluminal Administration in Rat Carotid Artery

Article DOI: 10.3791/52045-v • 09:41 min • December 23rd, 2014
December 23rd, 2014 •
1, 1
1Nanobioscience, State University of New York College of Nanoscale Science and Engineering (SUNY CNSE)

Chapitres

résumé
Automatic Translation

This protocol uses a balloon catheter to cause an intraluminal injury on the rat carotid artery and henceforth elicit neointimal hyperplasia. This is a well-established model for studying the mechanisms of vascular remodeling in response to injury. It is also widely used to determine the validity of potential therapeutic approaches.

Tags

Vascular Balloon Injury Intraluminal Administration Rat Carotid Artery Carotid Artery Balloon Injury Model Vascular Smooth Muscle Dedifferentiation Neointima Formation Vascular Remodeling Male Sprague-Dawley Rats Female Hormones Left Carotid Injury Inflated Balloon Denudes Endothelium Distends Vessel Wall Therapeutic Strategies Pharmacological Compounds Gene Transfer ShRNA Transfer Viral Particles Protein Expression Neointimal Thickening Proliferative Vascular Smooth Muscle Cells Cellular Analysis Molecular Analysis
Read Article

Get cutting-edge science videos from JoVE sent straight to your inbox every month.

Waiting X
Simple Hit Counter