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Reproducible Motor Deficit Following Aortic Occlusion in a Rat Model Of Spinal Cord Ischemia
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Reproducible Motor Deficit Following Aortic Occlusion in a Rat Model Of Spinal Cord Ischemia

Article DOI: 10.3791/55814-v • 08:11 min • July 22nd, 2017
July 22nd, 2017 •
1, 2, 2, 2, 2, 2, 2
1Department of Anesthesiology and Pain Medicine, SMG-SNU Boramae Medical Center, Seoul National University College of Medicine, Seoul, 2Department of Anesthesiology and Pain Medicine, SNU Bundang Hospital, Seongnamsi, Gyeonggido, Republic of Korea

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This study demonstrates the technique to make a minimally invasive and easily reproducible model of spinal cord ischemia in rats. Various degrees of hind limb motor deficit can be produced by controlling the aortic occlusion time.

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Reproducible Motor Deficit Aortic Occlusion Rat Model Spinal Cord Ischemia Technique Mi-Sun Lim Catheterization Arterial Pressure Monitoring Fogarty Catheter Femoral Artery Descending Thoracic Aorta Spinal Cord Ischemia Induction Carotid Artery Blood Reservoir Occlusion Time Deflation Of Balloon Reinfusion Of Blood Femur Catheter Removal Anesthesia Operating Table Ventral Position Isoflurane Inhalation Skin Incision Inguinal Area Black Silk Suture Arterial Pressure Monitoring Catheter Removal Wound Closure Hind-limb Motor Function Assessment
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