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Journal / Behavior / Depresyonun Hayvan Modelleri - Kronik Umutsuzluk…
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JoVE Journal Behavior
Depresyonun Hayvan Modelleri - Kronik Umutsuzluk Modeli (CDM)
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Depresyonun Hayvan Modelleri - Kronik Umutsuzluk Modeli (CDM)

Article DOI: 10.3791/62579-v • 05:47 min • September 23rd, 2021
September 23rd, 2021 •
1,2, 3,4, 1,5
1Department of Psychiatry and Psychotherapy, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, 2Berta-Ottenstein-Programme for Clinician Scientists, Faculty of Medicine, University of Freiburg, 3Centre National de la Recherche Scientifique (CNRS), Université de Strasbourg, Institut des Neurosciences Cellulaires et Intégratives, 4Department of Stereotactic and Functional Neurosurgery, Medical Center - University Freiburg, Faculty of Medicine, University of Freiburg, 5Center for Basics in Neuromodulation, Faculty of Medicine, University of Freiburg

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Depresyonun kronik umutsuzluk fare modeli (CDM), tekrarlayan zorla yüzme seanslarından ve bir okuma olarak başka bir gecikmeli yüzme aşamasından oluşur. Subkronik ve akut tedavi müdahalelerini değerlendirmek için değiştirilebilen, en az 4 hafta boyunca stabil olan kronik depresif benzeri bir durumun indüksiyonu için uygun bir modeli temsil eder.

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