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JoVE Journal Neuroscience
Generering af en reproducerbar model af mid-gestational maternal immunaktivering ved hjælp af Poly (I
Intracerebroventricular Injection of Amyloid-β Peptides in Normal Mice to Acutely Induce Alzheimer-like Cognitive Deficits
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Intracerebroventricular Injection of Amyloid-β Peptides in Normal Mice to Acutely Induce Alzheimer-like Cognitive Deficits
Electroconvulsive Seizures in Rats and Fractionation of Their Hippocampi to Examine Seizure-induced Changes in Postsynaptic Density Proteins
Journal (Neuroscience)
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Generering af en reproducerbar model af mid-gestational maternal immunaktivering ved hjælp af Poly (I: C) for at studere modtagelighed og modstandsdygtighed hos afkom

Article DOI: 10.3791/64095-v • 09:09 min • August 17th, 2022
August 17th, 2022 •
1, 1
1Center for Neuroscience, UC Davis

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Moderens infektion er en risikofaktor for neurodevelopmental lidelser. Musemodeller af moderens immunaktivering (MIA) kan belyse infektionens indvirkning på hjernens udvikling og funktion. Her gives generelle retningslinjer og en procedure til at producere pålideligt elastiske og modtagelige afkom udsat for MIA.

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Neurovidenskab udgave 186
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