Un modèle préclinique de transplantation cardiaque orthotopique chez des porcs miniatures de Bama à l’aide de la technique biatrial

1.1K vues

06:55 min

13 juin 2025

1.1K vues

Kai Xing¹^,²^,³ , Wei Wang¹^,² , Yuan Chang¹ , Shun Liu¹^,²^,³ , Peiyuan Li²^,⁴ , Xingchao Du¹^,²^,³ , Jiangping Song¹^,²^,³^,⁴^,⁵^,⁶

¹Department of Cardiac Surgery, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, ²Beijing Key Laboratory of Preclinical Research and Evaluation for Cardiovascular Implant Materials, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, ³Department of Cardiac Surgery, Fuwai Yunnan Hospital, Chinese Academy of Medical Sciences, Affiliated Cardiovascular Hospital of Kunming Medical University, ⁴State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, ⁵Shenzhen Key Laboratory of Cardiovascular Disease, Fuwai Hospital, Chinese Academy of Medical Sciences, ⁶Sanya Institute of China Agricultural University

Cette étude propose un modèle préclinique de transplantation cardiaque orthotopique chez des porcs miniatures Bama, en utilisant la technique biatriale. Le modèle est applicable à l’immunologie de la transplantation, à l’évaluation des médicaments et à l’optimisation des techniques chirurgicales, fournissant un soutien pour les applications cliniques de transplantation cardiaque.