Implantation d’un dispositif d’assistance ventriculaire gauche (LVAD) chez des porcs juvéniles de la race terrestre : un modèle d’implantation de LVAD pour l’insuffisance cardiaque pédiatrique

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05:18 min

16 janvier 2026

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Wei Wang^*¹^,² , Liying Wu^*³ , Xingchao Du¹^,²^,⁵ , Mengda Xu¹^,² , Yuan Chang¹^,² , Peiyuan Li¹^,² , Kai Xing¹^,²^,⁵ , Haisheng Chen³ , Jiangping Song¹^,²^,⁴^,⁵^,⁶^,⁷

¹Department of Cardiac Surgery, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, ²Beijing Key Laboratory of Preclinical Research and Evaluation for Cardiovascular Implant Materials, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, ³Guangzhou First People's Hospital, The Second Affiliated Hospital of South China University of Technology, ⁴Department of Cardiac Surgery, Fuwai Yunnan Hospital, Chinese Academy of Medical Sciences, Affiliated Cardiovascular Hospital of Kunming Medical University, ⁵State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, ⁶Shenzhen Key Laboratory of Cardiovascular Disease, Fuwai Hospital, Chinese Academy of Medical Sciences, ⁷Sanya Institute of China Agricultural University

^* These authors contributed equally

Cet article présente un protocole pour implanter le dispositif d’assistance ventriculaire gauche (LVAD) dans un porcelet. Ce modèle représente un moyen puissant d’étudier l’implantation du LVAD chez les enfants et de révéler le mécanisme du remodelage inverse ventriculaire dans le traitement du LVAD.