Cardiac Ct Imaging
Cardiac Ct Imaging - Related Videos
09:08
Combined SPECT and CT Imaging to Visualize Cardiac Functionality
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2023
Source: Alycia G. Berman, James A. Schaber, and Craig J. Goergen, Weldon School of Biomedical Engineering, Purdue University, West Lafayette, Indiana Here we will demonstrate the fundamentals of single-photon emission computed tomography/computed tomography (SPECT/CT) imaging using mice. The technique involves injecting a radionuclide into a mouse, imaging the animal after it is distributed throughout the body, and then reconstructing the produced images to create a volumetric dataset. This can...
11:37
Cardiac Magnetic Resonance Imaging
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2023
Source: Frederick W. Damen and Craig J. Goergen, Weldon School of Biomedical Engineering, Purdue University, West Lafayette, Indiana In this video, high field, small-bore magnetic resonance imaging (MRI) with physiological monitoring is demonstrated to acquire gated cine loops of the murine cardiovascular system. This procedure provides a basis for assessing left-ventricular function, visualizing vascular networks, and quantifying motion of organs due to respiration. Comparable small animal...
11:18
Micro-CT Imaging of a Mouse Spinal Cord
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2023
Source: Peiman Shahbeigi-Roodposhti and Sina Shahbazmohamadi, Biomedical Engineering Department, University of Connecticut, Storrs, Connecticut It's a little-known fact that the discovery and (inadvertent) use of X-rays garnered the first ever Nobel Prize in Physics. The famous X-ray image of Dr. Röntgen's wife's hand from 1895 that sent shock waves through the scientific community looks like most modern day 2D medical X-ray images. Though it is not the newest technology, X-ray absorption...
10:53
Functional Imaging of Brown Fat in Mice with 18F-FDG micro-PET/CT
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Cited by 37 •
2012
A method of functional imaging of mouse brown adipose tissue (BAT) is described in which cold-stimulated uptake of 18F-Fluorodeoxyglucose (FDG) in BAT is non-invasively assessed with a standardized micro-PET/CT protocol. This method is robust and sensitive to detect differences in BAT activities in mouse models.
09:14
Cardiac Magnetic Resonance Imaging at 7 Tesla
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Cited by 10 •
2019
The sensitivity gain inherent to ultrahigh field magnetic resonance holds promise for high spatial resolution imaging of the heart. Here, we describe a protocol customized for functional cardiovascular magnetic resonance (CMR) at 7 Tesla using an advanced multi-channel radio-frequency coil, magnetic field shimming and a triggering concept.
FAQs
Electrocardiographic (ECG) gating links image acquisition or reconstruction to a selected phase of the cardiac cycle. This reduces blurring caused by heart motion, making coronary vessels and cardiac structures easier to evaluate. In bioengineering, motion-controlled data are especially valuable when measurements are transferred into anatomical models or used to assess device placement.
Rotating X-ray measurements are computationally reconstructed into cross-sectional images and then combined into three-dimensional views. This reconstruction pathway converts projection data into spatially organized anatomy, allowing investigators to examine individual slices and overall vessel or chamber geometry. The resulting representations support quantitative analysis rather than relying only on visual inspection.
Iodinated contrast changes the visibility of blood-filled vessels and chambers during acquisition. By enhancing these structures, it helps distinguish vascular anatomy from surrounding tissues and supports assessment of coronary vessels. Its use is therefore tied to the imaging question: studies focused on vessel or chamber visualization may benefit from contrast-enhanced data, while contrast is not identified as mandatory for every scan.
High spatial resolution is important when the research question depends on small anatomic details. In cardiac CT imaging, it supports characterization of coronary plaque and more precise measurement of cardiac and vascular anatomy. Those measurements can then inform personalized treatment planning, image-based cardiovascular research, and engineering analyses that require patient-specific geometry.
A typical workflow begins by acquiring rotating X-ray measurements while recording the ECG, followed by reconstruction of gated cross-sectional images. Iodinated contrast may be administered when enhanced visualization of vessels or chambers is needed. The reconstructed data can then be reviewed as slices or three-dimensional images, depending on whether the goal is diagnosis, measurement, or modeling.
Researchers use these datasets to build computational models of the cardiovascular system from measured anatomy. The images provide patient-specific geometry and quantified cardiac or vascular structures as inputs for model development. This connection between clinical imaging and bioengineering analysis allows models to reflect an individual anatomy rather than relying only on generalized structural assumptions.
Cardiac CT imaging can inform the design and evaluation of implants and interventions by showing relevant cardiac and coronary anatomy in three dimensions. The same information can support treatment planning before an intervention and help researchers assess device concepts against patient-specific anatomy. Its value lies in linking structural measurements to engineering decisions and clinical needs.