Polymer Infusion
Polymer Infusion - Related Videos
02:34
Polymers
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2020
The word polymer is derived from the Greek words “poly” which means “many” and “mer” which means “parts”. Polymers are long chains of molecules composed of repeating units of smaller molecules, known as monomers. They either occur naturally, such as DNA and proteins, or can be constructed synthetically, like plastics. They have varied structural characteristics, such as linear chains, branched chains, or complex networks, that contribute to the properties that they exhibit. Additionally,...
08:18
A Model of Chronic Nutrient Infusion in the Rat
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Cited by 1 •
2013
A protocol for chronic infusions of glucose and Intralipid in rats is described. This model can be used to study the impact of nutrient excess on organ function and physiological parameters.
08:44
Tension Tests of Polymers
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2023
Source: Roberto Leon, Department of Civil and Environmental Engineering, Virginia Tech, Blacksburg, VA Polymeric materials are widely used in civil structures, with uses ranging from very soft sealants to more rigid pipes in water and wastewater systems. The most basic definition of a polymer is a molecular structure with repeating subunits. The term polymer comes from Greek, where "poly" means many, and "-mer" means basic unit. Monomers, or single mers, are the specific repeating units. With...
10:19
Neurodegeneration in an Animal Model of Chronic Amyloid-beta Oligomer Infusion Is Counteracted by Antibody Treatment Infused with Osmotic Pumps
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Cited by 11 •
2016
To study the effects of Aβo in vivo, we developed a model based on repeated hippocampal infusions of soluble Aβo coupled with continuous infusion of Aβo antibody (6E10) in the hippocampus using osmotic pumps to counteract the neurotoxic effect of Aβo.
08:12
Depolymerizable Olefinic Polymers Based on Fused-Ring Cyclooctene Monomers
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2022
Here, we describe protocols for the preparation of trans-cyclobutane fused cyclooctenes (tCBCO), their polymerization to prepare depolymerizable olefinic polymers, and the depolymerization of these polymers under mild conditions. Additionally, protocols for the preparation of depolymerizable networks and compression molding of rigid linear plastics based on this system are described.
FAQs
Low viscosity allows the liquid polymer to move into accessible spaces within tissues, cavities, or microvascular networks before solidification. This penetration is central to preserving internal architecture rather than only the specimen’s outer surface. In developmental biology, effective filling can reveal vessel patterns and anatomical connections that change as embryos or organs grow.
After the polymer reaches the spaces it can access, curing or polymerization converts the liquid into a stable cast or infiltrated matrix. That solid form maintains the spatial arrangement during later handling and observation. As a result, investigators can examine complex three-dimensional organization through microscopy or structural reconstruction without relying only on transient visibility in the original specimen.
Representation depends on whether the liquid can reach a particular space before curing occurs. The technique therefore records accessible cavities, tissue spaces, and microvascular pathways, while areas outside that accessible volume may not be represented. Recognizing this boundary helps researchers interpret a cast as a map of reachable internal architecture, not necessarily a complete view of every structure.
The basic workflow moves from introducing the liquid polymer into the specimen to allowing it to penetrate accessible spaces and then permitting curing or polymerization. Once stabilized, the resulting cast or infiltrated matrix can be examined by microscopy or used for structural reconstruction. This sequence links specimen preparation directly to later three-dimensional analysis.
The essential components are a biological specimen, a low-viscosity liquid polymer, and an analysis method suited to the stabilized structure. Microscopy can visualize the preserved arrangement, while structural reconstruction can represent it in three dimensions. Together, these approaches turn the cured cast or matrix into evidence for studying internal organization.
In developing embryos or organs, the method provides a durable representation for comparing growth-related changes. Researchers can examine how vessel patterns, tissue organization, and anatomical connections differ across developmental conditions or stages, then use microscopy or reconstruction to analyze those differences. Its value lies in making complex internal arrangements available for structural comparison.